Sonia Covaceuszach
Overview
Explore the profile of Sonia Covaceuszach including associated specialties, affiliations and a list of published articles.
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39
Citations
426
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Recent Articles
1.
Tosto R, Zimbone S, Sabatino G, Di Natale G, Giuffrida M, Tomasello M, et al.
Chembiochem
. 2024 Oct;
25(23):e202400431.
PMID: 39382238
Alzheimer's disease (AD) is a multifactorial form of dementia mainly affecting people in the elderly, but no effective cure is available. According to the amyloid hypothesis the aggregation of Amyloid-β...
2.
Mori M, Cocorullo M, Tresoldi A, Cazzaniga G, Gelain A, Stelitano G, et al.
Eur J Med Chem
. 2024 Jan;
265:116073.
PMID: 38169270
Blocking iron uptake and metabolism has been emerging as a promising therapeutic strategy for the development of novel antimicrobial compounds. Like all mycobacteria, M. abscessus (Mab) has evolved several countermeasures...
3.
Mori M, Ghirga F, Amato B, Secco L, Quaglio D, Romeo I, et al.
ACS Omega
. 2023 Sep;
8(36):32424-32431.
PMID: 37720761
HMGA proteins are intrinsically disordered (ID) chromatin architectural factors characterized by three DNA binding domains (AT-hooks) that allow them to bind into the DNA minor groove of AT-rich stretches. HMGA...
4.
Covaceuszach S, Lamba D
Biology (Basel)
. 2023 Mar;
12(3).
PMID: 36979056
Nerve Growth Factor (NGF), the prototype of the neurotrophin family, stimulates morphological differentiation and regulates neuronal gene expression by binding to TrkA and p75NTR receptors. It plays a critical role...
5.
Mori M, Stelitano G, Cazzaniga G, Gelain A, Tresoldi A, Cocorullo M, et al.
Pharmaceutics
. 2023 Feb;
15(2).
PMID: 36839823
Targeting pathogenic mechanisms, rather than essential processes, represents a very attractive approach for the development of new antimycobacterial drugs. In this context, iron acquisition routes have recently emerged as potentially...
6.
Paoletti F, Covaceuszach S, Cassetta A, Calabrese A, Novak U, Konarev P, et al.
Protein Sci
. 2023 Jan;
32(2):e4563.
PMID: 36605018
Nerve growth factor (NGF), the prototypical neurotrophic factor, is involved in the maintenance and growth of specific neuronal populations, whereas its precursor, proNGF, is involved in neuronal apoptosis. Binding of...
7.
Semrau M, Giachin G, Covaceuszach S, Cassetta A, Demitri N, Storici P, et al.
Nat Commun
. 2022 Oct;
13(1):6199.
PMID: 36261419
The delicate alternation between glycogen synthesis and degradation is governed by the interplay between key regulatory enzymes altering the activity of glycogen synthase and phosphorylase. Among these, the PP1 phosphatase...
8.
Covaceuszach S, Peche L, Konarev P, Grdadolnik J, Cattaneo A, Lamba D
Int J Mol Sci
. 2022 Jun;
23(12).
PMID: 35743044
The human genetic variant BDNF (V66M) represents the first example of neurotrophin family member that has been linked to psychiatric disorders. In order to elucidate structural differences that account for...
9.
Bez C, Covaceuszach S, Bertani I, Choudhary K, Venturi V
mSphere
. 2021 Oct;
6(6):e0085321.
PMID: 34704770
No abstract available.
10.
Paoletti F, Merzel F, Cassetta A, Ogris I, Covaceuszach S, Grdadolnik J, et al.
Comput Struct Biotechnol J
. 2021 Jun;
19:2938-2949.
PMID: 34136093
The Nerve Growth Factor (NGF) neurotrophin acts in the maintenance and growth of neuronal populations. Despite the detailed knowledge of NGF's role in neuron physiology, the structural and mechanistic determinants...