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Songcang Chen

Explore the profile of Songcang Chen including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 922
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Recent Articles
1.
Wang L, Wang C, Moriano J, Chen S, Zuo G, Cebrian-Silla A, et al.
Nature . 2025 Jan; PMID: 39779846
The development of the human neocortex is highly dynamic, involving complex cellular trajectories controlled by gene regulation. Here we collected paired single-nucleus chromatin accessibility and transcriptome data from 38 human...
2.
Wang L, Wang C, Moriano J, Chen S, Zuo G, Cebrian-Silla A, et al.
bioRxiv . 2024 Aug; PMID: 39131371
The development of the human neocortex is a highly dynamic process and involves complex cellular trajectories controlled by cell-type-specific gene regulation. Here, we collected paired single-nucleus chromatin accessibility and transcriptome...
3.
Chen S, Gemelga G, Yeghiazarians Y
Curr Hypertens Rep . 2022 Jun; 24(10):445-453. PMID: 35737199
Purpose Of The Review: Results from epidemiological studies suggest that vitamin D (VD) deficiency (VDD) may be a cause of hypertension (HTN). However, the results of randomized clinical trials (RCTs)...
4.
Chen S, Swier V, Boosani C, Radwan M, Agrawal D
Arterioscler Thromb Vasc Biol . 2016 Jun; 36(8):1651-9. PMID: 27255724
Objective: The role of vitamin D deficiency in coronary artery disease (CAD) progression is uncertain. Chronic inflammation in epicardial adipose tissue (EAT) has been implicated in the pathogenesis of CAD....
5.
Chen S, Villalta S, Agrawal D
J Bone Miner Res . 2015 Oct; 31(3):585-95. PMID: 26462119
Prospective epidemiological studies have consistently shown a relationship between vitamin D deficiency, insulin resistance, and type 2 diabetes mellitus (DM2). This is supported by recent trials showing that vitamin D...
6.
Chen S, Sun Y, Agrawal D
J Am Soc Hypertens . 2015 Oct; 9(11):885-901. PMID: 26419755
Essential hypertension (EH) results when the balance between vasoconstriction and vasodilation is shifted in favor of vasoconstriction. This balance is controlled by the interaction of genetic and epigenetic factors. When...
7.
Chen S, Agrawal D
Curr Hypertens Rep . 2015 Jan; 17(2):8. PMID: 25633669
Essential hypertension (EH) and its complications have had a severe impact on public health. However, the underlying mechanisms of the pathogenesis of EH remain largely unknown. Recent investigations, predominantly in...
8.
Ni W, Watts S, Ng M, Chen S, Glenn D, Gardner D
Hypertension . 2014 Sep; 64(6):1290-8. PMID: 25201890
Vitamin D deficiency has been associated with cardiovascular dysfunction. We evaluated the role of the vitamin D receptor (VDR) in vascular endothelial function, a marker of cardiovascular health, at baseline...
9.
Gardner D, Chen S, Glenn D
Am J Physiol Regul Integr Comp Physiol . 2013 Sep; 305(9):R969-77. PMID: 24026071
Vitamin D receptors (VDR) are found in cells throughout the cardiovascular system. A variety of experimental studies indicate that the liganded VDR may play an important role in controlling cardiac...
10.
Chen S, Gardner D
J Steroid Biochem Mol Biol . 2012 Sep; 136:150-5. PMID: 22989481
Vitamin D and its analogs have been suggested to have palliative effects in the cardiovascular system. We have examined the effects of co-administration of the vitamin D receptor agonist, paricalcitol,...