Sonali Chaturvedi
Overview
Explore the profile of Sonali Chaturvedi including associated specialties, affiliations and a list of published articles.
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23
Citations
195
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Recent Articles
1.
Chaturvedi S, Pablo M, Wolf M, Rosas-Rivera D, Calia G, Kumar A, et al.
Cell
. 2023 Apr;
186(9):2036-2037.
PMID: 37116472
No abstract available.
2.
Chaturvedi S, Beutler N, Vasen G, Pablo M, Chen X, Calia G, et al.
Proc Natl Acad Sci U S A
. 2022 Sep;
119(39):e2204624119.
PMID: 36074824
The high transmissibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a primary driver of the COVID-19 pandemic. While existing interventions prevent severe disease, they exhibit mixed efficacy in...
3.
Chaturvedi S, Beutler N, Pablo M, Vasen G, Chen X, Calia G, et al.
bioRxiv
. 2022 Aug;
PMID: 35982679
Significance: COVID-19 vaccines are exceptionally effective in preventing severe disease and death, but they have mixed efficacy in preventing virus transmission, consistent with established literature that parenteral vaccines for other...
4.
Chaturvedi S, Pablo M, Wolf M, Rosas-Rivera D, Calia G, Kumar A, et al.
Cell
. 2022 May;
185(12):2086-2102.e22.
PMID: 35561685
Across biological scales, gene-regulatory networks employ autorepression (negative feedback) to maintain homeostasis and minimize failure from aberrant expression. Here, we present a proof of concept that disrupting transcriptional negative feedback...
5.
Chaturvedi S, Vasen G, Pablo M, Chen X, Beutler N, Kumar A, et al.
Cell
. 2021 Nov;
184(25):6022-6036.e18.
PMID: 34838159
Viral-deletion mutants that conditionally replicate and inhibit the wild-type virus (i.e., defective interfering particles, DIPs) have long been proposed as single-administration interventions with high genetic barriers to resistance. However, theories...
6.
Desai R, Chen X, Martin B, Chaturvedi S, Hwang D, Li W, et al.
Science
. 2021 Jul;
373(6557).
PMID: 34301855
Stochastic fluctuations in gene expression ("noise") are often considered detrimental, but fluctuations can also be exploited for benefit (e.g., dither). We show here that DNA base excision repair amplifies transcriptional...
7.
Chaturvedi S, Rao A
Methods Mol Biol
. 2020 Aug;
2170:213-218.
PMID: 32797461
Protein-protein interactions (PPI) are vital in regulating the biological and physiological functions in a given cell or organism. Proteomics, in conjunction with bioinformatic tools, represents the study involving the characterization...
8.
Chaturvedi S, Engel R, Weinberger L
Front Cell Infect Microbiol
. 2020 Jul;
10:265.
PMID: 32670890
Herpes simplex virus-1 (HSV-1) is a significant human pathogen. Upon infection, HSV-1 expresses its immediate early (IE) genes, and the IE transcription factor ICP4 (infectious cell protein-4) plays a pivotal...
9.
Chaturvedi S, Klein J, Vardi N, Bolovan-Fritts C, Wolf M, Du K, et al.
Proc Natl Acad Sci U S A
. 2020 Jul;
117(29):17240-17248.
PMID: 32632017
Probabilistic bet hedging, a strategy to maximize fitness in unpredictable environments by matching phenotypic variability to environmental variability, is theorized to account for the evolution of various fate-specification decisions, including...
10.
Chaturvedi S, Rao A
Curr Opin Virol
. 2018 Aug;
33:113-119.
PMID: 30165268
Plant pathogenic single strand positive-sense RNA viruses with the tripartite genome are classified into two families: Bromoviridae and Virgaviridae. Family Bromoviridae contains four genera Bromo, Cucumo, Alfamo, and Ilarviruses characterized...