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Soma Ray

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Articles 26
Citations 749
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Recent Articles
1.
Home P, Ghosh A, Kumar R, Ray S, Gunewardena S, Kumar R, et al.
bioRxiv . 2024 Jul; PMID: 39071312
During embryonic development the placental vasculature acts as a major hematopoietic niche, where endothelial to hematopoietic transition ensures emergence of hematopoietic stem cells (HSCs). However, the molecular mechanisms that regulate...
2.
Kumar R, Kumar R, Ganguly A, Ghosh A, Ray S, Islam M, et al.
bioRxiv . 2024 Jul; PMID: 39026770
Methyltransferase-like 3 (METTL3), the catalytic enzyme of methyltransferase complex for m6A methylation of RNA, is essential for mammalian development. However, the importance of METTL3 in human placentation remains largely unexplored....
3.
Ghosh A, Kumar R, Kumar R, Ray S, Saha A, Roy N, et al.
Proc Natl Acad Sci U S A . 2024 Feb; 121(8):e2310502121. PMID: 38346193
The placenta establishes a maternal-fetal exchange interface to transport nutrients and gases between the mother and the fetus. Establishment of this exchange interface relies on the development of multinucleated syncytiotrophoblasts...
4.
Ray S, Saha A, Ghosh A, Roy N, Kumar R, Meinhardt G, et al.
Proc Natl Acad Sci U S A . 2022 Aug; 119(36):e2204069119. PMID: 36037374
Healthy progression of human pregnancy relies on cytotrophoblast (CTB) progenitor self-renewal and its differentiation toward multinucleated syncytiotrophoblasts (STBs) and invasive extravillous trophoblasts (EVTs). However, the underlying molecular mechanisms that fine-tune...
5.
Saha B, Ganguly A, Home P, Bhattacharya B, Ray S, Ghosh A, et al.
Proc Natl Acad Sci U S A . 2020 Jul; 117(30):17864-17875. PMID: 32669432
Early pregnancy loss affects ∼15% of all implantation-confirmed human conceptions. However, evolutionarily conserved molecular mechanisms that regulate self-renewal of trophoblast progenitors and their association with early pregnancy loss are poorly...
6.
Bhattacharya B, Home P, Ganguly A, Ray S, Ghosh A, Islam M, et al.
Proc Natl Acad Sci U S A . 2020 Jun; 117(25):14280-14291. PMID: 32513715
In utero mammalian development relies on the establishment of the maternal-fetal exchange interface, which ensures transportation of nutrients and gases between the mother and the fetus. This exchange interface is...
7.
Milano-Foster J, Ray S, Home P, Ganguly A, Bhattacharya B, Bajpai S, et al.
J Biol Chem . 2019 Oct; 294(46):17301-17313. PMID: 31591264
A successful pregnancy is critically dependent upon proper placental development and function. During human placentation, villous cytotrophoblast (CTB) progenitors differentiate to form syncytiotrophoblasts (SynTBs), which provide the exchange surface between...
8.
Kumar R, Ray S, Home P, Saha B, Bhattacharya B, Wilkins H, et al.
Development . 2018 Sep; 145(19). PMID: 30201685
Early mammalian development is crucially dependent on the establishment of oxidative energy metabolism within the trophectoderm (TE) lineage. Unlike the inner cell mass, TE cells enhance ATP production via mitochondrial...
9.
Ranger A, Ray S, Szak S, Dearth A, Allaire N, Murray R, et al.
Neurol Neuroimmunol Neuroinflamm . 2017 Dec; 5(1):e417. PMID: 29259995
Objective: To evaluate whether the anti-LINGO-1 antibody has immunomodulatory effects. Methods: Human peripheral blood mononuclear cells (hPBMCs), rat splenocytes, and rat CD4 T cells were assessed to determine whether LINGO-1...
10.
Gupta S, Richards S, Amaravadi L, Piccoli S, DeSilva B, Pillutla R, et al.
Bioanalysis . 2017 Dec; 9(24):1967-1996. PMID: 29205064
The 2017 11th Workshop on Recent Issues in Bioanalysis took place in Los Angeles/Universal City, California, on 3-7 April 2017 with participation of close to 750 professionals from pharmaceutical/biopharmaceutical companies,...