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Soline Bourgeois

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Articles 37
Citations 869
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Recent Articles
1.
Bourgeois S, Houillier P
Pflugers Arch . 2024 Mar; 476(4):517-531. PMID: 38448728
The disposal of ammonia, the main proton buffer in the urine, is important for acid-base homeostasis. Renal ammonia excretion is the predominant contributor to renal net acid excretion, both under...
2.
Bourgeois S, Kovacikova J, Bugarski M, Bettoni C, Gehring N, Hall A, et al.
J Am Soc Nephrol . 2023 Nov; 35(1):7-21. PMID: 37990364
Significance Statement: In the kidney, the B1 H + -ATPase subunit is mostly expressed in intercalated cells (IC). Its importance in acid-secreting type A ICs is evident in patients with...
3.
Verissimo T, Dalga D, Arnoux G, Sakhi I, Faivre A, Auwerx H, et al.
Am J Physiol Renal Physiol . 2023 Apr; 324(6):F532-F543. PMID: 37102687
Phosphoenolpyruvate carboxykinase 1 (PCK1 or PEPCK-C) is a cytosolic enzyme converting oxaloacetate to phosphoenolpyruvate, with a potential role in gluconeogenesis, ammoniagenesis, and cataplerosis in the liver. Kidney proximal tubule cells...
4.
Pastor Arroyo E, Yassini N, Sakiri E, Russo G, Bourgeois S, Mohebbi N, et al.
Clin Sci (Lond) . 2022 Apr; 136(8):557-577. PMID: 35389462
Chronic kidney disease (CKD) affects approximately 10-13% of the population worldwide and halting its progression is a major clinical challenge. Metabolic acidosis is both a consequence and a possible driver...
5.
Ugrica M, Bettoni C, Bourgeois S, Daryadel A, Pastor-Arroyo E, Gehring N, et al.
Nephrol Dial Transplant . 2021 Jan; PMID: 33515264
Background: Phosphate intake has increased in the last decades due to a higher consumption of processed foods. This higher intake is detrimental for patients with chronic kidney disease, increasing mortality...
6.
Bourgeois S, Wagner C
Curr Opin Nephrol Hypertens . 2020 Nov; 30(1):131-137. PMID: 33186222
Purpose Of Review: Pendrin resides on the luminal membrane of type B intercalated cells in the renal collecting tubule system mediating the absorption of chloride in exchange for bicarbonate. In...
7.
Ghazi S, Bourgeois S, Gomariz A, Bugarski M, Haenni D, Martins J, et al.
FASEB J . 2020 May; 34(6):8510-8525. PMID: 32367531
Alpha intercalated cells (αICs) in the kidney collecting duct (CD) belong to a family of mitochondria rich cells (MRCs) and have a crucial role in acidifying the urine via apical...
8.
Wagner C, Silva P, Bourgeois S
Semin Nephrol . 2019 Jul; 39(4):340-352. PMID: 31300090
Acid-base balance is critical for normal life. Acute and chronic disturbances impact cellular energy metabolism, endocrine signaling, ion channel activity, neuronal activity, and cardiovascular functions such as cardiac contractility and...
9.
Fearn A, Allison B, Rice S, Edwards N, Halbritter J, Bourgeois S, et al.
Physiol Rep . 2018 Jun; 6(12):e13715. PMID: 29924459
Mutations in SLC34A1, encoding the proximal tubular sodium-phosphate transporter NaPi-IIa, may cause a range of clinical phenotypes including infantile hypercalcemia, a proximal renal Fanconi syndrome, which are typically autosomal recessive,...
10.
Bourgeois S, Bettoni C, Baron S, Wagner C
Cell Physiol Biochem . 2018 May; 47(3):1095-1107. PMID: 29843146
Background/aims: Homozygous mutations or deletion of the ATP6V1B1 gene encoding for the B1 subunit of the vacuolar H+-ATPase leads to distal renal tubular acidosis in man and mice. In humans,...