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Solene Grosdidier

Explore the profile of Solene Grosdidier including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 282
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Recent Articles
1.
Callegaro G, Kunnen S, Trairatphisan P, Grosdidier S, Niemeijer M, den Hollander W, et al.
Arch Toxicol . 2021 Oct; 95(12):3745-3775. PMID: 34626214
Mechanism-based risk assessment is urged to advance and fully permeate into current safety assessment practices, possibly at early phases of drug safety testing. Toxicogenomics is a promising source of mechanisms-revealing...
2.
James G, Collin E, Lawrance M, Mueller A, Podhorna J, Zaremba-Pechmann L, et al.
Soc Psychiatry Psychiatr Epidemiol . 2020 Jun; 56(3):409-416. PMID: 32494994
Purpose: Real-world studies to describe the use of first, second and third line therapies for the management and symptomatic treatment of dementia are lacking. This retrospective cohort study describes the...
3.
Newby D, Prieto-Alhambra D, Duarte-Salles T, Ansell D, Pedersen L, van der Lei J, et al.
Alzheimers Res Ther . 2020 Apr; 12(1):38. PMID: 32252806
Background: Inflammatory processes have been shown to play a role in dementia. To understand this role, we selected two anti-inflammatory drugs (methotrexate and sulfasalazine) to study their association with dementia...
4.
Faner R, Gutierrez-Sacristan A, Castro-Acosta A, Grosdidier S, Gan W, Sanchez-Mayor M, et al.
Eur Respir J . 2015 Aug; 46(4):1001-10. PMID: 26250499
The frequent occurrence of comorbidities in patients with chronic obstructive pulmonary disease (COPD) suggests that they may share pathobiological processes and/or risk factors.To explore these possibilities we compared the clinical...
5.
Gutierrez-Sacristan A, Grosdidier S, Valverde O, Torrens M, Bravo A, Pinero J, et al.
Bioinformatics . 2015 May; 31(18):3075-7. PMID: 25964630
Unlabelled: PsyGeNET (Psychiatric disorders and Genes association NETwork) is a knowledge platform for the exploratory analysis of psychiatric diseases and their associated genes. PsyGeNET is composed of a database and...
6.
Grosdidier S, Ferrer A, Faner R, Pinero J, Roca J, Cosio B, et al.
Respir Res . 2014 Sep; 15:111. PMID: 25248857
Background: Patients with chronic obstructive pulmonary disease (COPD) often suffer concomitant disorders that worsen significantly their health status and vital prognosis. The pathogenic mechanisms underlying COPD multimorbidities are not completely...
7.
Masone D, Grosdidier S
Comput Biol Chem . 2014 Feb; 49:1-6. PMID: 24509001
In biophysics, the structural prediction of protein-protein complexes starting from the unbound form of the two interacting monomers is a major difficulty. Although current computational docking protocols are able to...
8.
Lensink M, Moal I, Bates P, Kastritis P, Melquiond A, Karaca E, et al.
Proteins . 2013 Oct; 82(4):620-32. PMID: 24155158
We report the first assessment of blind predictions of water positions at protein-protein interfaces, performed as part of the critical assessment of predicted interactions (CAPRI) community-wide experiment. Groups submitting docking...
9.
Pallara C, Jimenez-Garcia B, Perez-Cano L, Romero-Durana M, Solernou A, Grosdidier S, et al.
Proteins . 2013 Aug; 81(12):2192-200. PMID: 23934865
In addition to protein-protein docking, this CAPRI edition included new challenges, like protein-water and protein-sugar interactions, or the prediction of binding affinities and ΔΔG changes upon mutation. Regarding the standard...
10.
Grosdidier S, Fernandez-Recio J
Expert Opin Drug Discov . 2013 Mar; 4(6):673-86. PMID: 23489159
Background: Computational approaches such as docking and scoring are becoming routine in drug discovery as a complement to other more traditional techniques. However, so far, computer drug design methods have...