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Soheil Aghamohammadzadeh

Explore the profile of Soheil Aghamohammadzadeh including associated specialties, affiliations and a list of published articles. Areas
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Citations 448
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Recent Articles
1.
Levian B, Hou Y, Tang X, Bainvoll L, Zheng K, Badarinarayana V, et al.
Mol Ther Nucleic Acids . 2024 Oct; 35(4):102334. PMID: 39391765
Recessive dystrophic epidermolysis bullosa (RDEB) and junctional epidermolysis bullosa (JEB) are lethal blistering skin disorders resulting from mutations in genes coding for type VII collagen () and laminin 332 (,...
2.
Chen J, Thrasher K, Fu L, Wang W, Aghamohammadzadeh S, Wen H, et al.
Am J Physiol Lung Cell Mol Physiol . 2023 Apr; 324(6):L756-L770. PMID: 37014818
Ten percent of cystic fibrosis (CF) patients carry a premature termination codon (PTC); no mutation-specific therapies exist for these individuals. ELX-02, a synthetic aminoglycoside, suppresses translation termination at PTCs (i.e.,...
3.
Henry A, Aghamohammadzadeh S, Samaroo H, Chen Y, Mou K, Needle E, et al.
Hum Mol Genet . 2015 Aug; 24(21):6013-28. PMID: 26251043
Lysosomal dysfunction plays a central role in the pathogenesis of several neurodegenerative disorders, including Parkinson's disease (PD). Several genes linked to genetic forms of PD, including leucine-rich repeat kinase 2...
4.
Aghamohammadzadeh S, Smaczynska-de Rooij I, Ayscough K
PLoS One . 2014 Jul; 9(7):e103311. PMID: 25072293
Clathrin-mediated endocytosis (CME) is a well characterized pathway in both yeast and mammalian cells. An increasing number of alternative endocytic pathways have now been described in mammalian cells that can...
5.
Smaczynska-de Rooij I, Allwood E, Mishra R, Booth W, Aghamohammadzadeh S, Goldberg M, et al.
Traffic . 2011 Nov; 13(2):317-28. PMID: 22082017
Dynamins are a conserved family of proteins involved in many membrane fusion and fission events. Previously, the dynamin-related protein Vps1 was shown to localize to endocytic sites, and yeast carrying...
6.
Pearson C, Ohyama K, Manning L, Aghamohammadzadeh S, Sang H, Placzek M
Development . 2011 May; 138(12):2613-24. PMID: 21610037
The infundibulum links the nervous and endocrine systems, serving as a crucial integrating centre for body homeostasis. Here we describe that the chick infundibulum derives from two subsets of anterior...
7.
Smaczynska-de Rooij I, Allwood E, Aghamohammadzadeh S, Hettema E, Goldberg M, Ayscough K
J Cell Sci . 2010 Sep; 123(Pt 20):3496-506. PMID: 20841380
Dynamins are a conserved family of proteins involved in membrane fusion and fission. Although mammalian dynamins are known to be involved in several membrane-trafficking events, the role of dynamin-1 in...
8.
Aghamohammadzadeh S, Ayscough K
Nat Cell Biol . 2009 Jul; 11(8):1039-42. PMID: 19597484
Key features of clathrin-mediated endocytosis have been conserved across evolution. However, endocytosis in Saccharomyces cerevisiae is completely dependent on a functional actin cytoskeleton, whereas actin appears to be less critical...
9.
Law C, Kirby R, Aghamohammadzadeh S, Furley A
Development . 2008 Jun; 135(14):2361-71. PMID: 18550718
When the axons of primary sensory neurons project into the embryonic mammalian spinal cord, they bifurcate and extend rostrocaudally before sending collaterals to specific laminae according to neuronal subclass. The...
10.
Gheorghe D, Aghamohammadzadeh S, Smaczynska-de Rooij I, Allwood E, Winder S, Ayscough K
J Biol Chem . 2008 Apr; 283(22):15037-46. PMID: 18400761
The yeast SM22 homologue Scp1 has previously been shown to act as an actin-bundling protein in vitro. In cells, Scp1 localizes to the cortical actin patches that form as part...