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Sohei Tanabe

Explore the profile of Sohei Tanabe including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 216
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Recent Articles
1.
Ishii H, Shigematsu R, Takemoto S, Ishikawa Y, Mizobe F, Nomura M, et al.
Curr Drug Metab . 2024 Sep; 25(7):489-504. PMID: 39238378
Objective: Osilodrostat, used to treat Cushing's disease, exhibits an anabolic effect, leading to its classification as a prohibited substance in horseracing and equestrian sports. This study reports the characterization of...
2.
Ishii H, Shigematsu R, Takemoto S, Ishikawa Y, Mizobe F, Nomura M, et al.
Bioanalysis . 2024 Sep; 16(17-18):947-958. PMID: 39235065
The use of osilodrostat, developed as a medication for Cushing's disease but categorized as an anabolic agent, is banned in horses by both the International Federation of Horseracing Authorities and...
3.
Ishii H, Ishikawa Y, Mizobe F, Nomura M, Yamanaka T, Tanabe S, et al.
Rapid Commun Mass Spectrom . 2024 Feb; 38(5):e9695. PMID: 38355879
Rationale: Osilodrostat is an inhibitor of 11-beta-hydroxylase (CYP11B) and is used for the treatment of Cushing's disease but also categorized as an anabolic agent. The use of osilodrostat is prohibited...
4.
Ito S, Hosaka T, Yano W, Itou T, Yasumura M, Shimizu Y, et al.
Physiol Rep . 2018 Mar; 6(5). PMID: 29520981
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) exert their antidiabetic effects by promoting urinary glucose excretion. Nutrition therapy is obviously important, but little is known about the interactions between SGLT2i agents and...
5.
Yano W, Inoue N, Ito S, Itou T, Yasumura M, Yoshinaka Y, et al.
J Diabetes Investig . 2016 Nov; 8(2):155-160. PMID: 27860391
Aims/introduction: Dipeptidyl peptidase-4 inhibitors are used for treatment of patients with type 2 diabetes. In addition to glycemic control, these agents showed beneficial effects on lipid metabolism in clinical trials....
6.
Kaneko Y, Ohta M, Inoue T, Mizuno K, Isobe T, Tanabe S, et al.
Sci Rep . 2016 Jan; 6:19640. PMID: 26782355
Ripasudil hydrochloride hydrate (K-115), a specific Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor, was the first ophthalmic solution developed for the treatment of glaucoma and ocular hypertension in Japan. Topical...
7.
Miyosawa K, Watanabe Y, Murakami K, Murakami T, Shibata H, Iwashita M, et al.
Am J Physiol Endocrinol Metab . 2015 May; 309(2):E177-90. PMID: 26015437
Despite significant reduction of cardiovascular events by statin treatment, substantial residual risk persists, driving emerging needs for the development of new therapies. We identified a novel cholesteryl ester transfer protein...
8.
Maejima T, Inoue T, Kanki Y, Kohro T, Li G, Ohta Y, et al.
PLoS One . 2014 May; 9(5):e96005. PMID: 24797675
Statins exert atheroprotective effects through the induction of specific transcriptional factors in multiple organs. In endothelial cells, statin-dependent atheroprotective gene up-regulation is mediated by Kruppel-like factor (KLF) family transcription factors....
9.
Isobe T, Mizuno K, Kaneko Y, Ohta M, Koide T, Tanabe S
Curr Eye Res . 2014 Feb; 39(8):813-22. PMID: 24502505
Purpose: To evaluate the topical instillation of K-115, a selective Rho-associated coiled coil-containing protein kinase (ROCK) inhibitor, on intraocular pressure (IOP), ocular distribution, and aqueous humor dynamics in experimental animals....
10.
Nishimura J, Ohmichi K, Wato E, Saito T, Takashima K, Tanaka T, et al.
Exp Toxicol Pathol . 2013 Mar; 65(7-8):961-71. PMID: 23462190
To investigate the adrenal toxicity of a novel inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase, compound X (CX), histopathological examinations, fat staining, adrenal cholesterol measurement, blood biochemistry, plasma corticosterone and ACTH measurement,...