Soham Dibyachintan
Overview
Explore the profile of Soham Dibyachintan including associated specialties, affiliations and a list of published articles.
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5
Citations
34
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Recent Articles
1.
Dibyachintan S, Dube A, Bradley D, Lemieux P, Dionne U, Landry C
Nat Commun
. 2025 Feb;
16(1):1530.
PMID: 39934115
Paralogous genes are often functionally redundant for long periods of time. While their functions are preserved, paralogs accumulate cryptic changes in sequence and expression, which could modulate the impact of...
2.
Rouleau F, Dube A, Gagnon-Arsenault I, Dibyachintan S, Pageau A, Despres P, et al.
PLoS Genet
. 2024 Apr;
20(4):e1011252.
PMID: 38683847
Pneumocystis jirovecii is a fungal pathogen that causes pneumocystis pneumonia, a disease that mainly affects immunocompromised individuals. This fungus has historically been hard to study because of our inability to...
3.
Dibyachintan S, Dube A, Bradley D, Lemieux P, Dionne U, Landry C
bioRxiv
. 2024 Mar;
PMID: 38464075
Paralogous genes are often redundant for long periods of time before they diverge in function. While their functions are preserved, paralogous proteins can accumulate mutations that, through epistasis, could impact...
4.
Apte S, Bhutda S, Ghosh S, Sharma K, Barton T, Dibyachintan S, et al.
Sci Adv
. 2023 Mar;
9(12):eade1851.
PMID: 36947610
Sensing of pathogens by ubiquitination is a critical arm of cellular immunity. However, universal ubiquitination targets on microbes remain unidentified. Here, using in vitro, ex vivo, and in vivo studies,...
5.
Dube A, Dandage R, Dibyachintan S, Dionne U, Despres P, Landry C
Methods Mol Biol
. 2022 May;
2477:237-259.
PMID: 35524121
Deep mutational scanning (DMS) generates mutants of a protein of interest in a comprehensive manner. CRISPR-Cas9 technology enables large-scale genome editing with high efficiency. Using both DMS and CRISPR-Cas9 therefore...
6.
Dionne U, Bourgault E, Dube A, Bradley D, Chartier F, Dandage R, et al.
Nat Commun
. 2021 Mar;
12(1):1597.
PMID: 33712617
Protein-protein interactions (PPIs) between modular binding domains and their target peptide motifs are thought to largely depend on the intrinsic binding specificities of the domains. The large family of SRC...