Sohail Malik
Overview
Explore the profile of Sohail Malik including associated specialties, affiliations and a list of published articles.
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46
Citations
2726
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Recent Articles
1.
Zhao H, Li J, Xiang Y, Malik S, Vartak S, Veronezi G, et al.
Mol Cell
. 2024 Jul;
84(14):2648-2664.e10.
PMID: 38955181
The essential Mediator (MED) coactivator complex plays a well-understood role in regulation of basal transcription in all eukaryotes, but the mechanism underlying its role in activator-dependent transcription remains unknown. We...
2.
Malik S, Roeder R
Nat Rev Genet
. 2023 Aug;
24(11):767-782.
PMID: 37532915
The RNA polymerase II (Pol II) pre-initiation complex (PIC) is a critical node in eukaryotic transcription regulation, and its formation is the major rate-limiting step in transcriptional activation. Diverse cellular...
3.
Nakadai T, Shimada M, Ito K, Cevher M, Chu C, Kumegawa K, et al.
Cell Res
. 2023 Jan;
33(2):165-183.
PMID: 36646760
Estrogen-related receptors (ERRα/β/γ) are orphan nuclear receptors that function in energy-demanding physiological processes, as well as in development and stem cell maintenance, but mechanisms underlying target gene activation by ERRs...
4.
Malik S, Guermah M, Yuan C, Wu W, Yamamura S, Roeder R
Mol Cell Biol
. 2022 Oct;
42(11):e0035922.
PMID: 36255214
No abstract available.
5.
Lee Y, Ito K, Pi W, Lin I, Chu C, Malik S, et al.
Proc Natl Acad Sci U S A
. 2021 Feb;
118(6).
PMID: 33542097
The chimeric transcription factor E2A-PBX1, containing the N-terminal activation domains of E2A fused to the C-terminal DNA-binding domain of PBX1, results in 5% of pediatric acute lymphoblastic leukemias (ALL). We...
6.
Williams R, Guarecuco R, Gates L, Barrows D, Passarelli M, Carey B, et al.
Cell Metab
. 2020 Apr;
31(4):852-861.e6.
PMID: 32268116
Activating transcription factor 4 (ATF4) is a master transcriptional regulator of the integrated stress response (ISR) that enables cell survival under nutrient stress. The mechanisms by which ATF4 couples metabolic...
7.
Zhang Y, Pavlov A, Malik S, Chen H, Kim N, Li Z, et al.
PLoS One
. 2020 Apr;
15(3):e0230670.
PMID: 32231397
The human positive coactivator 4 (PC4) was originally identified as a multi-functional cofactor capable of mediating transcription activation by diverse gene- and tissue-specific activators. Recent studies suggest that PC4 might...
8.
Hajibandeh S, Hajibandeh S, Hobbs N, Shah J, Harris M, Watton L, et al.
J Perioper Pract
. 2019 Oct;
30(7-8):221-228.
PMID: 31573381
Aims: To investigate whether an intraperitoneal contamination index (ICI) derived from combined preoperative levels of C-reactive protein, lactate, neutrophils, lymphocytes and albumin could predict the extent of intraperitoneal contamination in...
9.
Pham P, Malik S, Mak C, Calabrese P, Roeder R, Goodman M
Nucleic Acids Res
. 2019 Oct;
47(20):10815-10829.
PMID: 31566237
Activation-induced deoxycytidine deaminase (AID) initiates somatic hypermutation (SHM) in immunoglobulin variable (IgV) genes to produce high-affinity antibodies. SHM requires IgV transcription by RNA polymerase II (Pol II). A eukaryotic transcription...
10.
Hajibandeh S, Hajibandeh S, Thompson J, Mohammed J, Smith C, Prince J, et al.
Gastroenterol Hepatol Bed Bench
. 2019 Jun;
12(2):116-123.
PMID: 31191835
Aim: To determine whether combined laboratory and ultrasonography results can be used to select patients for biliary tract imaging (BTI) or intervention. Background: Despite ongoing research, selection of patients with...