Sofie Van Gassen
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Explore the profile of Sofie Van Gassen including associated specialties, affiliations and a list of published articles.
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36
Citations
2883
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Recent Articles
1.
Quintelier K, Willemsen M, Bosteels V, Aerts J, Saeys Y, Van Gassen S
Cytometry A
. 2025 Jan;
PMID: 39871681
Cytometry is a single cell, high-dimensional, high-throughput technique that is being applied across a range of disciplines. However, many elements alongside the data acquisition process might give rise to technical...
2.
Couckuyt A, Rombaut B, Saeys Y, Van Gassen S
Bioinformatics
. 2024 Apr;
40(4).
PMID: 38632080
Motivation: We describe a new Python implementation of FlowSOM, a clustering method for cytometry data. Results: This implementation is faster than the original version in R, better adapted to work...
3.
van Spronsen M, Van Gassen S, Duetz C, Westers T, Saeys Y, van de Loosdrecht A
Leukemia
. 2024 Mar;
38(6):1365-1377.
PMID: 38459168
Myelodysplastic neoplasms (MDS) encompass haematological malignancies, which are characterised by dysplasia, ineffective haematopoiesis and the risk of progression towards acute myeloid leukaemia (AML). Myelodysplastic neoplasms are notorious for their heterogeneity:...
4.
Liechti T, Van Gassen S, Beddall M, Ballard R, Iftikhar Y, Du R, et al.
Cell Rep Methods
. 2023 Oct;
3(10):100619.
PMID: 37883924
High-dimensional flow cytometry is the gold standard to study the human immune system in large cohorts. However, large sample sizes increase inter-experimental variation because of technical and experimental inaccuracies introduced...
5.
Dietz M, Quintelier K, van Kooten J, de Boer N, Vink M, Brandt-Kerkhof A, et al.
J Immunother Cancer
. 2023 Aug;
11(8).
PMID: 37536940
Background: Malignant peritoneal mesothelioma (MPM) is an aggressive malignancy with a poor prognosis. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) improves survival outcomes, but recurrence rates remain high. Dendritic...
6.
Mortier C, Quintelier K, De Craemer A, Renson T, Deroo L, Dumas E, et al.
Arthritis Rheumatol
. 2023 Jun;
75(11):1969-1982.
PMID: 37293832
Objective: Patients with spondyloarthritis (SpA) often present with microscopic signs of gut inflammation, a risk factor for progressive disease. We investigated whether mucosal innate-like T cells are involved in dysregulated...
7.
Bosteels V, Marechal S, De Nolf C, Rennen S, Maelfait J, Tavernier S, et al.
Sci Immunol
. 2023 May;
8(83):eadd3955.
PMID: 37172103
Dendritic cells (DCs) mature in an immunogenic or tolerogenic manner depending on the context in which an antigen is perceived, preserving the balance between immunity and tolerance. Whereas the pathways...
8.
Panovska D, Nazari P, Cole B, Creemers P, Derweduwe M, Solie L, et al.
Cell Mol Life Sci
. 2023 May;
80(6):147.
PMID: 37171617
Background: Functional profiling of freshly isolated glioblastoma (GBM) cells is being evaluated as a next-generation method for precision oncology. While promising, its success largely depends on the method to evaluate...
9.
van Spronsen M, Horrevorts S, Cali C, Westers T, Van Gassen S, Saeys Y, et al.
Leukemia
. 2023 Feb;
37(3):702-707.
PMID: 36759685
No abstract available.
10.
Rybakowska P, Van Gassen S, Martorell Marugan J, Quintelier K, Saeys Y, Alarcon-Riquelme M, et al.
STAR Protoc
. 2022 Nov;
3(4):101697.
PMID: 36353363
Mass cytometry (MC) is a powerful large-scale immune monitoring technology. To maximize MC data quality, we present a protocol for whole blood analysis together with an R package, Cyto Quality...