Sofie Lundgren
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Explore the profile of Sofie Lundgren including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
156
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Recent Articles
1.
Lundgren S, Huuhtanen J, Keranen M, Feng X, Patel B, Ryland G, et al.
Sci Transl Med
. 2025 Feb;
17(787):eadl6758.
PMID: 40009697
Immune aplastic anemia (AA) is a life-threatening bone marrow failure disorder driven by an autoimmune T cell attack against hematopoietic stem and progenitor cells (HSPCs). However, the exact autoantigen targets...
2.
Lundgren S, Myllymaki M, Jarvinen T, Keranen M, Theodoropoulos J, Smolander J, et al.
Sci Adv
. 2024 Jun;
10(23):eadj0787.
PMID: 38848368
Somatic mutations in T cells can cause cancer but also have implications for immunological diseases and cell therapies. The mutation spectrum in nonmalignant T cells is unclear. Here, we examined...
3.
Lundgren S, Keranen M, Wartiovaara-Kautto U, Myllymaki M
Semin Hematol
. 2022 Sep;
59(3):167-173.
PMID: 36115694
Inherited bone marrow failure syndromes (IBMFS) are a heterogeneous group of genetic disorders characterized by insufficient blood cell production and increased risk of transformation to myeloid malignancies. While genetically diverse,...
4.
Kelkka T, Tyster M, Lundgren S, Feng X, Kerr C, Hosokawa K, et al.
Leukemia
. 2022 Aug;
36(9):2317-2327.
PMID: 35927326
In immune aplastic anemia (IAA), severe pancytopenia results from the immune-mediated destruction of hematopoietic stem cells. Several autoantibodies have been reported, but no clinically applicable autoantibody tests are available for...
5.
Pagliuca S, Gurnari C, Awada H, Kishtagari A, Kongkiatkamon S, Terkawi L, et al.
Blood
. 2021 Nov;
138(26):2781-2798.
PMID: 34748628
Idiopathic aplastic anemia (IAA) is a rare autoimmune bone marrow failure (BMF) disorder initiated by a human leukocyte antigen (HLA)-restricted T-cell response to unknown antigens. As in other autoimmune disorders,...
6.
Lundgren S, Keranen M, Kankainen M, Huuhtanen J, Walldin G, Kerr C, et al.
Leukemia
. 2021 Mar;
35(5):1365-1379.
PMID: 33785863
The prevalence and functional impact of somatic mutations in nonleukemic T cells is not well characterized, although clonal T-cell expansions are common. In immune-mediated aplastic anemia (AA), cytotoxic T-cell expansions...
7.
Savola P, Lundgren S, Keranen M, Almusa H, Ellonen P, Leirisalo-Repo M, et al.
Blood Cancer J
. 2021 Feb;
11(2):36.
PMID: 33597539
No abstract available.
8.
Savola P, Martelius T, Kankainen M, Huuhtanen J, Lundgren S, Koski Y, et al.
Haematologica
. 2020 Dec;
105(12):2757-2768.
PMID: 33256375
Common variable immunodeficiency and other late-onset immunodeficiencies often co-manifest with autoimmunity and lymphoproliferation. The pathogenesis of most cases is elusive, as only a minor subset harbors known monogenic germline causes....
9.
Kim D, Park G, Huuhtanen J, Lundgren S, Khajuria R, Hurtado A, et al.
Nat Commun
. 2020 May;
11(1):2246.
PMID: 32382059
Graft versus host disease (GvHD) is the main complication of allogeneic hematopoietic stem cell transplantation (HSCT). Here we report studies of a patient with chronic GvHD (cGvHD) carrying persistent CD4...
10.
Savola P, Lundgren S, Keranen M, Almusa H, Ellonen P, Leirisalo-Repo M, et al.
Blood Cancer J
. 2018 Aug;
8(8):69.
PMID: 30061683
No abstract available.