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Sofie Ingvast

Explore the profile of Sofie Ingvast including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 118
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Recent Articles
1.
Yngve E, Ingvast S, Korsgren O, Yu D
Ups J Med Sci . 2025 Feb; 130. PMID: 39981200
Background: Oncolytic viruses are promising tools for immune stimulatory gene therapy of cancer, but their clinical effect on solid tumors have so far been limited. Transduction of the target tumor...
2.
Tegehall A, Ingvast S, Krogvold L, Dahl-Jorgensen K, Korsgren O
Acta Diabetol . 2024 May; 61(9):1117-1127. PMID: 38717484
Aims/hypothesis: Defensins play a crucial role in the innate immune system's first defense against microbial threats. However, little is known about the defensin system in the pancreas, especially in relation...
3.
Puuvuori E, Shen Y, Hulsart-Billstrom G, Mitran B, Zhang B, Cheung P, et al.
J Nucl Med . 2023 Dec; 65(2):294-299. PMID: 38050119
Rheumatoid arthritis (RA) is the most common inflammatory joint disease, and early diagnosis is key for effective disease management. CD69 is one of the earliest cell surface markers seen at...
4.
Wegrzyniak O, Zhang B, Rokka J, Rosestedt M, Mitran B, Cheung P, et al.
EJNMMI Radiopharm Chem . 2023 Sep; 8(1):23. PMID: 37733133
Background: Platelet-derived growth factor receptor beta (PDGFRβ) is a receptor overexpressed on activated hepatic stellate cells (aHSCs). Positron emission tomography (PET) imaging of PDGFRβ could potentially allow the quantification of...
5.
Puuvuori E, Chiodaroli E, Estrada S, Cheung P, Lubenow N, Sigfridsson J, et al.
J Nucl Med . 2022 Sep; 64(3):423-429. PMID: 36109184
Today, there is a lack of clinically available imaging techniques to detect and quantify specific immune cell populations. Neutrophils are one of the first immune cells at the site of...
6.
Puuvuori E, Liggieri F, Velikyan I, Chiodaroli E, Sigfridsson J, Romelin H, et al.
EJNMMI Res . 2022 Apr; 12(1):19. PMID: 35394238
Purpose: In the characterization of severe lung diseases, early detection of specific inflammatory cells could help to monitor patients' response to therapy and increase chances of survival. Macrophages contribute to...
7.
Rosestedt M, Velikyan I, Rosenstrom U, Estrada S, Aberg O, Weis J, et al.
Nucl Med Biol . 2020 Dec; 93:54-62. PMID: 33321470
Introduction: Pathological formation of fibrosis, is an important feature in many diseases. Fibrosis in liver and pancreas has been associated to metabolic disease including type 1 and 2 diabetes. The...
8.
Stenwall A, Ingvast S, Skog O, Korsgren O
Islets . 2019 Jun; 11(4):89-101. PMID: 31242128
The gut microbiota can play a role in pancreatitis and, likely, in the development of type 1 diabetes (T1D). Anti-microbial peptides and secretory proteins are important mediators of the innate...
9.
Jonsson A, Yngve E, Karlsson M, Ingvast S, Skog O, Korsgren O
J Histochem Cytochem . 2018 Sep; 67(2):99-105. PMID: 30265185
Viral infection of the insulin-producing cells in the pancreas has been proposed in the etiology of type 1 diabetes. Protein kinase R (PKR) is a cytoplasmic protein activated through phosphorylation...
10.