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Sofie Demeyer

Explore the profile of Sofie Demeyer including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 786
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Recent Articles
1.
Aertgeerts M, Meyers S, Gielen O, Lamote J, Dewaele B, Tajdar M, et al.
Hemasphere . 2025 Feb; 9(2):e70085. PMID: 39944233
High hyperdiploid (HeH) B-cell acute lymphoblastic leukemia (B-ALL) is the most prevalent subtype of childhood ALL. This leukemia is characterized by trisomies and tetrasomies of specific chromosomes and additional point...
2.
Lauwereins L, Van Thillo Q, Demeyer S, Mentens N, Provost S, Jacobs K, et al.
Leukemia . 2025 Jan; 39(3):568-576. PMID: 39838044
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological disease originating from the malignant transformation of T-cell progenitors, caused by the accumulation of genetic aberrations. One-fifth of T-ALL patients are...
3.
Aertgeerts M, Meyers S, Demeyer S, Segers H, Cools J
Mol Diagn Ther . 2024 Aug; 28(6):727-744. PMID: 39190087
Acute lymphoblastic leukemia (ALL) is the most common cancer in children. ALL originates from precursor lymphocytes that acquire multiple genomic changes over time, including chromosomal rearrangements and point mutations. While...
4.
Meyers S, Gielen O, Cools J, Demeyer S
Haematologica . 2024 May; 109(10):3167-3181. PMID: 38813729
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive type of leukemia caused by accumulation of multiple genetic alterations in T-cell progenitors. However, for many genes it remains unknown how their...
5.
Veloso A, Bleuart A, Conrard L, Orban T, Bruyr J, Cabochette P, et al.
BMC Biol . 2024 Feb; 22(1):51. PMID: 38414014
Background: Lymphangiogenesis, the formation of lymphatic vessels, is tightly linked to the development of the venous vasculature, both at the cellular and molecular levels. Here, we identify a novel role...
6.
Pollenus E, Possemiers H, Knoops S, Prenen F, Vandermosten L, Thienpont C, et al.
PLoS Pathog . 2024 Jan; 20(1):e1011929. PMID: 38236930
Plasmodium parasites cause malaria, a global health disease that is responsible for more than 200 million clinical cases and 600 000 deaths each year. Most deaths are caused by various...
7.
Meyers S, Demeyer S, Cools J
J Hematol Oncol . 2023 Oct; 16(1):107. PMID: 37875911
The CRISPR genome editing technology has revolutionized the way gene function is studied. Genome editing can be achieved in single genes or for thousands of genes simultaneously in sensitive genetic...
8.
Altea-Manzano P, Doglioni G, Liu Y, Cuadros A, Nolan E, Fernandez-Garcia J, et al.
Nat Cancer . 2023 Feb; 4(3):344-364. PMID: 36732635
Metabolic rewiring is often considered an adaptive pressure limiting metastasis formation; however, some nutrients available at distant organs may inherently promote metastatic growth. We find that the lung and liver...
9.
van Gils N, Verhagen H, Broux M, Martianez T, Denkers F, Vermue E, et al.
iScience . 2022 Sep; 25(9):105013. PMID: 36097617
Although chemotherapy induces complete remission in the majority of acute myeloid leukemia (AML) patients, many face a relapse. This relapse is caused by survival of chemotherapy-resistant leukemia (stem) cells (measurable...
10.
Rossi M, Altea-Manzano P, Demicco M, Doglioni G, Bornes L, Fukano M, et al.
Nature . 2022 Aug; 609(7927):E8. PMID: 36042336
No abstract available.