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Slavena Vylkova

Explore the profile of Slavena Vylkova including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 841
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Recent Articles
1.
Kapitan M, Niemiec M, Millet N, Brandt P, Chowdhury M, Czapka A, et al.
bioRxiv . 2024 Sep; PMID: 39314435
The fungus and the Gram-positive bacterium share mucosal niches in the human body. As opportunistic pathogens, both are found to expand population size during dysbiosis, and can cause severe systemic...
2.
Bottcher B, Kienast S, Leufken J, Eggers C, Sharma P, Leufken C, et al.
Microbiol Spectr . 2024 Apr; 12(5):e0425522. PMID: 38587411
tRNA modifications play important roles in maintaining translation accuracy in all domains of life. Disruptions in the tRNA modification machinery, especially of the anticodon stem loop, can be lethal for...
3.
Rebai Y, Wagner L, Gnaien M, Hammer M, Kapitan M, Niemiec M, et al.
Microorganisms . 2023 Aug; 11(8). PMID: 37630490
is a pathobiont of the gastrointestinal tract. It can contribute to the diversity of the gut microbiome without causing harmful effects. When the immune system is compromised, can damage intestinal...
4.
Hader A, Schauble S, Gehlen J, Thielemann N, Buerfent B, Schuller V, et al.
Nat Commun . 2023 Jun; 14(1):3239. PMID: 37277347
Innate immune responses vary by pathogen and host genetics. We analyze quantitative trait loci (eQTLs) and transcriptomes of monocytes from 215 individuals stimulated by fungal, Gram-negative or Gram-positive bacterial pathogens....
5.
Brandt P, Mirhakkak M, Wagner L, Driesch D, Moslinger A, Fander P, et al.
Microbiol Spectr . 2023 Apr; 11(3):e0049823. PMID: 37097196
Candida auris, a multidrug-resistant human fungal pathogen that causes outbreaks of invasive infections, emerged as four distinct geographical clades. Previous studies identified genomic and proteomic differences in nutrient utilization on...
6.
Luther C, Brandt P, Vylkova S, Dandekar T, Muller T, Dittrich M
Front Cell Infect Microbiol . 2023 Apr; 13:1108235. PMID: 37082713
Fungal infections are a major global health burden where is among the most common fungal pathogen in humans and is a common cause of invasive candidiasis. Fungal phenotypes, such as...
7.
Garbe E, Thielemann N, Hohner S, Kumar A, Vylkova S, Kurzai O, et al.
Microbiol Spectr . 2023 Feb; :e0025323. PMID: 36786567
The formation of hyphae is a key virulence attribute of Candida albicans as they are required for adhesion to and invasion of host cells, and ultimately deep-tissue dissemination. Hyphae also...
8.
Garbe E, Gerwien F, Driesch D, Muller T, Bottcher B, Graler M, et al.
mSystems . 2022 Oct; 7(6):e0053922. PMID: 36264075
The yeast-to-hypha transition is a key virulence attribute of the opportunistic human fungal pathogen Candida albicans, since it is closely tied to infection-associated processes such as tissue invasion and escape...
9.
Bottcher B, Driesch D, Kruger T, Garbe E, Gerwien F, Kniemeyer O, et al.
NPJ Biofilms Microbiomes . 2022 Oct; 8(1):78. PMID: 36224215
Candida albicans biofilm maturation is accompanied by enhanced expression of amino acid acquisition genes. Three state-of-the-art omics techniques were applied to detail the importance of active amino acid uptake during...
10.
Alonso-Roman R, Last A, Mirhakkak M, Sprague J, Moller L, Grossmann P, et al.
Nat Commun . 2022 Jun; 13(1):3192. PMID: 35680868
Intestinal microbiota dysbiosis can initiate overgrowth of commensal Candida species - a major predisposing factor for disseminated candidiasis. Commensal bacteria such as Lactobacillus rhamnosus can antagonize Candida albicans pathogenicity. Here,...