Siyuan Chai
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Explore the profile of Siyuan Chai including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
121
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Recent Articles
1.
Excellent Laccase Mimic Activity of Cu-Melamine and Its Applications in the Degradation of Congo Red
Chai S, Huang E, Zeng J, Shi Y, Zhang J, Zhang X
Appl Biochem Biotechnol
. 2025 Feb;
PMID: 39891857
Copper-based nanozyme has shown the superior in the oxidase-like activities due to its electron transfer ability between the Cu(I) and Cu(II) sites during the catalytic reactions. Herein, a Cu(I)-MOF (Cu-Mel)...
2.
Zhou L, Yu L, Song S, Wang Y, Zhu Q, Li M, et al.
Cell Rep
. 2025 Jan;
44(2):115242.
PMID: 39864061
Arginine methylation is a common post-translational modification that plays critical roles in many biological processes. However, the existence of arginine demethylases that remove the modification has not been fully established....
3.
Zhu Q, Li J, Sun H, Fan Z, Hu J, Chai S, et al.
Proc Natl Acad Sci U S A
. 2024 Oct;
121(44):e2408354121.
PMID: 39446384
Aerobic glycolysis and immune evasion are two key hallmarks of cancer. However, how these two features are mechanistically linked to promote tumor growth is not well understood. Here, we show...
4.
Lin B, Chai S, Zhang Q, Lu Y, Hu J, Zhang J, et al.
Mol Pharm
. 2023 Nov;
21(1):102-112.
PMID: 37994899
O-linked--acetylglucosaminylation (O-GlcNAcylation) plays a key role in hepatocellular carcinoma (HCC) development, and the inhibition of O-GlcNAcylation has therapeutic potential. To decrease the systemic adverse events and increase targeting, we used...
5.
Zhu Q, Wang H, Chai S, Xu L, Lin B, Yi W, et al.
Proc Natl Acad Sci U S A
. 2023 Mar;
120(13):e2216796120.
PMID: 36943877
Programmed-death ligand 1 (PD-L1) and its receptor programmed cell death 1 (PD-1) mediate T cell-dependent immunity against tumors. The abundance of cell surface PD-L1 is a key determinant of the...
6.
Wang Y, Shao J, Wang P, Chen L, Ying M, Chai S, et al.
Front Oncol
. 2021 Nov;
11:721460.
PMID: 34765542
Background: Our aim was to establish a deep learning radiomics method to preoperatively evaluate regional lymph node (LN) staging for hilar cholangiocarcinoma (HC) patients. Methods And Materials: Of the 179...
7.
Zhang H, Chai S, Chen L, Wang Y, Cheng Y, Fang Q, et al.
Front Oncol
. 2021 Jul;
11:611738.
PMID: 34221954
Introduction: Hepatic sarcomatoid carcinoma (HSC) is a rare type of liver cancer with a high malignant grade and poor prognosis. This study compared the clinical characteristics and magnetic resonance imaging...
8.
Wehbe R, Sheng J, Dutta S, Chai S, Dravid A, Barutcu S, et al.
Radiology
. 2020 Nov;
299(1):E167-E176.
PMID: 33231531
Background There are characteristic findings of coronavirus disease 2019 (COVID-19) on chest images. An artificial intelligence (AI) algorithm to detect COVID-19 on chest radiographs might be useful for triage or...