Sivakumar Arumugam
Overview
Explore the profile of Sivakumar Arumugam including associated specialties, affiliations and a list of published articles.
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29
Citations
181
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Recent Articles
1.
Sharma D, Arumugam S
Mol Divers
. 2025 Feb;
PMID: 39921842
Aberrant activation of the Wnt/β-catenin signaling pathway, primarily driven by APC mutation and AXIN degradation via Tankyrase, contributes significantly to colorectal cancer (CRC) progression and metastasis. The accumulation of β-catenin,...
2.
Hussain M, Sharma S, Kumari A, Kamran A, Bahl G, Bisht A, et al.
Epigenomics
. 2024 Nov;
16(23-24):1453-1464.
PMID: 39601046
Neurofibromatosis (NF) is identified as genetic disorder characterized by multiple tumors on nerve tissues. NF1 is the most prevalent form, identified by neurofibromas and skin changes. NF1 is the most...
3.
Ramalingam P, Premkumar T, Sundararajan V, Hussain M, Arumugam S
Discov Oncol
. 2024 Oct;
15(1):592.
PMID: 39453574
Mutant KRAS promotes the proliferation, metastasis, and aggressiveness of various cancers including pancreatic ductal adenocarcinoma (PDAC), non-small cell lung cancer (NSCLC), and colorectal adenocarcinoma (CRC) respectively. Mutant KRAS therapeutics are...
4.
Shah M, Arumugam S
Mol Divers
. 2024 Jul;
28(4):2263-2287.
PMID: 38954070
Cardiovascular disease is a chronic inflammatory disease with high mortality rates. TNF-alpha is pro-inflammatory and associated with the disease, but current medications have adverse effects. Therefore, efficient inhibitors are urgently...
5.
Ramalingam P, Elangovan S, Mekala J, Arumugam S
Front Cell Dev Biol
. 2024 Mar;
12:1386102.
PMID: 38550382
Cancer has become a serious health burden that results in high incidence and mortality rates every year, mainly due to various molecular alterations inside the cell. Liver X receptors (LXRs)...
6.
Majeed M, Nagabhushanam K, Arumugam S, Chadalavada N, Seepana J, Annamalai T, et al.
Front Pediatr
. 2024 Jan;
11:1338126.
PMID: 38269290
Objectives: Acute diarrhea in children is generally managed by replacing the lost fluid with oral rehydration solution (ORS). Probiotic supplementation has been reported to reduce the severity of diarrhea. In...
7.
Ramalingam P, Arumugam S
3 Biotech
. 2023 Oct;
13(11):350.
PMID: 37780803
Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-023-03767-w.
8.
Ramalingam P, Arumugam S
Med Oncol
. 2023 Aug;
40(10):283.
PMID: 37644143
Mutant KRAS-induced tumorigenesis is highly involved in the progression of pancreatic, lung, and breast cancer. Comparatively, KRAS G12D and KRAS G12C are the most frequent mutations that promote cancer progression...
9.
Ramalingam P, Priyadharshini A, Emerson I, Arumugam S
Front Med (Lausanne)
. 2023 Jul;
10:1107128.
PMID: 37396909
Background: Mutant KRAS-induced tumorigenesis is prevalent in lung, colon, and pancreatic ductal adenocarcinomas. For the past 3 decades, KRAS mutants seem undruggable due to their high-affinity GTP-binding pocket and smooth...
10.
Majeed M, Nagabhushanam K, Mundkur L, Paulose S, Divakar H, Rao S, et al.
Medicine (Baltimore)
. 2023 Jun;
102(20):e33751.
PMID: 37335737
Background: Probiotics are known to rebalance the gut microbiota in dysbiotic individuals, but their impact on the gut microbiome of healthy individuals is seldom studied. The current study is designed...