Sirintra Nakjang
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Explore the profile of Sirintra Nakjang including associated specialties, affiliations and a list of published articles.
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41
Citations
1136
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Recent Articles
1.
Aptullahoglu E, Nakjang S, Wallis J, Marr H, Marshall S, Willmore E, et al.
Biomedicines
. 2024 Jul;
12(7).
PMID: 39061962
Chronic lymphocytic leukemia (CLL) is a genetically and clinically diverse hematological cancer affecting middle-aged and elderly individuals. Novel targeted therapy options are needed for patients who relapse following initial responses...
2.
Alebady Z, Azizyan M, Nakjang S, Lishman-Walker E, Al-Kharaif D, Walker S, et al.
Cancers (Basel)
. 2023 Jul;
15(14).
PMID: 37509260
The methyltransferase KMT5A has been proposed as an oncogene in prostate cancer and therefore represents a putative therapeutic target. To confirm this hypothesis, we have performed a microarray study on...
3.
Permtermsin C, Lalchungnunga H, Nakjang S, Casement J, Ogle L, Reeves H, et al.
Int J Mol Sci
. 2023 Apr;
24(7).
PMID: 37047360
Hepatocellular carcinoma (HCC), the most common type of liver cancer, has very poor outcomes. Current therapies often have low efficacy and significant toxicities. Thus, there is a critical need for...
4.
Issa H, Swart L, Rasouli M, Ashtiani M, Nakjang S, Jyotsana N, et al.
Leukemia
. 2023 Feb;
37(4):820-834.
PMID: 36823395
A hallmark of acute myeloid leukaemias (AMLs) are chromosomal rearrangements that give rise to novel leukaemia-specific fusion genes. Most of these fusion genes are both initiating and driving events in...
5.
Sinclair P, Cranston R, Raninga P, Cheng J, Hanna R, Hawking Z, et al.
Leukemia
. 2023 Jan;
37(3):636-649.
PMID: 36670235
A common problem in the study of human malignancy is the elucidation of cancer driver mechanisms associated with recurrent deletion of regions containing multiple genes. Taking B-cell acute lymphoblastic leukaemia...
6.
Pal D, Blair H, Parker J, Hockney S, Beckett M, Singh M, et al.
Cell Rep Med
. 2022 Aug;
3(8):100717.
PMID: 35977468
Leukemia cells re-program their microenvironment to augment blast proliferation and enhance treatment resistance. Means of clinically targeting such niche-driven treatment resistance remain ambiguous. We develop human induced pluripotent stem cell...
7.
Tirtakusuma R, Szoltysek K, Milne P, Grinev V, Ptasinska A, Chin P, et al.
Blood
. 2022 Jul;
140(17):1875-1890.
PMID: 35839448
The fusion gene MLL/AF4 defines a high-risk subtype of pro-B acute lymphoblastic leukemia. Relapse can be associated with a lineage switch from acute lymphoblastic to acute myeloid leukemia, resulting in...
8.
Zaki M, Mahdi A, Patman G, Whitehead A, Mauricio J, McCain M, et al.
Sci Rep
. 2021 Aug;
11(1):16727.
PMID: 34408183
The prevalence of obesity and non-alcoholic fatty liver disease (NAFLD) associated hepatocellular carcinoma (HCC) is rising, even in the absence of cirrhosis. We aimed to develop a murine model that...
9.
Mansur M, Furness C, Nakjang S, Enshaei A, Alpar D, Colman S, et al.
Cancer Med
. 2021 Jun;
10(14):4864-4873.
PMID: 34080325
Background: Treatment on risk adapted intensive pediatric protocols has improved outcome for teenagers and young adults (TYA) with T-cell acute lymphoblastic leukemia (T-ALL). Understanding the biology of disease in this...
10.
Grinev V, Barneh F, Ilyushonak I, Nakjang S, Smink J, van Oort A, et al.
Nat Commun
. 2021 Jan;
12(1):520.
PMID: 33483506
The fusion oncogene RUNX1/RUNX1T1 encodes an aberrant transcription factor, which plays a key role in the initiation and maintenance of acute myeloid leukemia. Here we show that the RUNX1/RUNX1T1 oncogene...