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Josef Vormoor

Explore the profile of Josef Vormoor including associated specialties, affiliations and a list of published articles. Areas
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Articles 60
Citations 1284
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Recent Articles
1.
George S, Lynn C, Stankunaite R, Hughes D, Sauer C, Chalker J, et al.
Cancer Discov . 2024 Dec; PMID: 39693475
We profiled a large heterogenous cohort of matched diagnostic-relapse tumour tissue and paired plasma-derived cell free DNA (cfDNA) from patients with relapsed and progressive solid tumours of childhood. Tissue and...
2.
Bozovic Spasojevic I, Ferrari A, De Munter J, Gamble A, Konsoulova-Kirova A, Rizvi K, et al.
Tumori . 2023 Jul; 109(6):546-554. PMID: 37486101
Background: It is well documented that traditional health care models do not meet the specific needs of Adolescents and Young Adults (AYA) cancer patients. Methods: We explore a map of...
3.
Verwaaijen E, van der Torre P, Vormoor J, Pieters R, Fiocco M, Hartman A, et al.
Cancers (Basel) . 2023 Jan; 15(1). PMID: 36612316
Sarcopenia in pediatric hemato-oncology patients is undesirable because of the consequences it may have for treatment continuation and outcome, physical abilities and participation in daily life. An easy-to-use screening tool...
4.
Pal D, Blair H, Parker J, Hockney S, Beckett M, Singh M, et al.
Cell Rep Med . 2022 Aug; 3(8):100717. PMID: 35977468
Leukemia cells re-program their microenvironment to augment blast proliferation and enhance treatment resistance. Means of clinically targeting such niche-driven treatment resistance remain ambiguous. We develop human induced pluripotent stem cell...
5.
Tirtakusuma R, Szoltysek K, Milne P, Grinev V, Ptasinska A, Chin P, et al.
Blood . 2022 Jul; 140(17):1875-1890. PMID: 35839448
The fusion gene MLL/AF4 defines a high-risk subtype of pro-B acute lymphoblastic leukemia. Relapse can be associated with a lineage switch from acute lymphoblastic to acute myeloid leukemia, resulting in...
6.
Bomken S, Enshaei A, Schwalbe E, Mikulasova A, Dai Y, Zaka M, et al.
Haematologica . 2022 Apr; 108(3):717-731. PMID: 35484682
Rarely, immunophenotypically immature B-cell precursor acute lymphoblastic leukemia (BCP-ALL) carries an immunoglobulin- MYC rearrangement (IG-MYC-r). This can result in diagnostic confusion with Burkitt lymphoma/leukemia and use of individualized treatment schedules...
7.
Menne T, Slade D, Savage J, Johnson S, Irving J, Kearns P, et al.
BMJ Open . 2022 Mar; 12(3):e059872. PMID: 35246426
Introduction: Event-free survival rates at 15 years for paediatric patients with relapsed/refractory acute lymphoblastic leukaemia (ALL) are 30%-50%, with 5-year survival for adult patients only 20%. Many patients with newly...
8.
Brivio E, Baruchel A, Beishuizen A, Bourquin J, Brown P, Cooper T, et al.
Eur J Cancer . 2022 Feb; 164:1-17. PMID: 35121370
Despite improved outcomes achieved in the last decades for children with newly diagnosed leukaemia and lymphoma, treatment of patients with refractory/relapsed disease remains a challenge. The cure rate is still...
9.
Van der Zwet J, Buijs-Gladdines J, Cordo V, Debets D, Smits W, Chen Z, et al.
Leukemia . 2021 May; 35(12):3394-3405. PMID: 34007050
(Patho-)physiological activation of the IL7-receptor (IL7R) signaling contributes to steroid resistance in pediatric T-cell acute lymphoblastic leukemia (T-ALL). Here, we show that activating IL7R pathway mutations and physiological IL7R signaling...
10.
Wolfs T, Attarbaschi A, Balduzzi A, Bernardo M, Bomken S, Borkhardt A, et al.
Hemasphere . 2020 Sep; 4(5):e465. PMID: 32984769
No abstract available.