Siqun L Zheng
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Explore the profile of Siqun L Zheng including associated specialties, affiliations and a list of published articles.
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38
Citations
1527
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Recent Articles
1.
Chase B, Frigerio R, Rubin S, Semenov I, Meyers S, Mark A, et al.
J Clin Med
. 2025 Jan;
14(2).
PMID: 39860542
: Migraine is a common neurological disorder with highly variable characteristics. While genome-wide association studies have identified genetic risk factors that implicate underlying pathways, the influence of genetic susceptibility on...
2.
Chase B, Frigerio R, Rubin S, Franada T, Semenov I, Meyers S, et al.
J Clin Med
. 2024 Nov;
13(21).
PMID: 39518622
: Genome-wide association studies (GWASs) demonstrate a complex genetic landscape for migraine risk. Migraine polygenic risk scores (PRSs) developed from GWAS data may have utility for predicting disease course. We...
3.
Chase B, Semenov I, Rubin S, Meyers S, Mark A, Makhlouf T, et al.
Headache
. 2023 Dec;
64(1):68-92.
PMID: 38071464
Objective: To evaluate response to anti-calcitonin gene-related peptide (CGRP) migraine preventives in a real-world community cohort of persons living with migraine and to identify clinical and genetic characteristics associated with...
4.
Mendes A, Lu J, Kaur H, Zheng S, Xu J, Hicks J, et al.
Cancer
. 2022 Mar;
128(12):2269-2280.
PMID: 35333400
Background: B7 homolog 3 (B7-H3) is an immunomodulatory molecule that is highly expressed in prostate cancer (PCa) and belongs to the B7 superfamily, which includes PD-L1. Immunotherapies (antibodies, antibody-drug conjugates,...
5.
Huang D, Wu Y, Ye D, Qi J, Liu F, Helfand B, et al.
Asian J Androl
. 2020 Jan;
22(5):539-543.
PMID: 31929198
To evaluate whether prostate volume (PV) would provide additional predictive utility to the prostate health index (phi) for predicting prostate cancer (PCa) or clinically significant prostate cancer, we designed a...
6.
Yu H, Shi Z, Lin X, Bao Q, Jia H, Wei J, et al.
Prostate
. 2019 Oct;
80(1):83-87.
PMID: 31634418
Background: Several polygenic risk score (PRS) methods are available for measuring the cumulative effect of multiple risk-associated single nucleotide polymorphisms (SNPs). Their performance in predicting risk at the individual level...
7.
Shi Z, Yu H, Wu Y, Lin X, Bao Q, Jia H, et al.
Cancer Med
. 2019 Apr;
8(6):3196-3205.
PMID: 30968590
Background: Genetic risk score (GRS) is an odds ratio (OR)-weighted and population-standardized method for measuring cumulative effect of multiple risk-associated single nucleotide polymorphisms (SNPs). We hypothesize that GRS is a...
8.
Shi Z, Yu H, Wu Y, Ford M, Perschon C, Wang C, et al.
Clin Genet
. 2018 Nov;
95(2):302-309.
PMID: 30460685
Single nucleotide polymorphism (SNP)-based genetic risk score (GRS) and APOE genotype are both important in risk prediction of Alzheimer's disease (AD); however, the interaction between GRS and APOE has not...
9.
Na R, Wu Y, Jiang G, Yu H, Lin X, Wang M, et al.
BJU Int
. 2018 May;
122(5):808-813.
PMID: 29727914
Objectives: To perform a systematic evaluation of whether germline DNA repair gene mutations in bladder cancer (BCa) are associated with increased risk of BCa and aggressive disease. Materials And Methods:...
10.
Na R, Ye D, Qi J, Liu F, Helfand B, Brendler C, et al.
Prostate
. 2017 Jul;
77(11):1221-1229.
PMID: 28664580
Background: The performance of prostate health index (phi) in predicting prostate biopsy outcomes has been well established for patients with prostate-specific antigen (PSA) values between 2 and 10 ng/mL. However,...