Sion W Jones
Overview
Explore the profile of Sion W Jones including associated specialties, affiliations and a list of published articles.
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5
Citations
283
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Recent Articles
1.
Velez I, Hien T, Green J, Martin A, Sharma H, Rousell V, et al.
Lancet Child Adolesc Health
. 2021 Dec;
6(2):86-95.
PMID: 34871570
Background: Single-dose tafenoquine 300 mg is approved for Plasmodium vivax malaria relapse prevention in patients at least 16 years old. We aimed to determine appropriate oral tafenoquine paediatric dosing regimens,...
2.
Ackert J, Mohamed K, Slakter J, El-Harazi S, Berni A, Gevorkyan H, et al.
Drug Saf
. 2019 Jun;
42(9):1103-1114.
PMID: 31187437
Introduction: Tafenoquine has been recently registered for the prevention of relapse in Plasmodium vivax malaria. Objective: This study assessed the pharmacodynamic effects of 300-mg single-dose tafenoquine on the retina. Methods:...
3.
Llanos-Cuentas A, Lacerda M, Hien T, Velez I, Namaik-Larp C, Chu C, et al.
N Engl J Med
. 2019 Jan;
380(3):229-241.
PMID: 30650326
Background: Tafenoquine, a single-dose therapy for Plasmodium vivax malaria, has been associated with relapse prevention through the clearance of P. vivax parasitemia and hypnozoites, termed "radical cure." Methods: We performed...
4.
Lacerda M, Llanos-Cuentas A, Krudsood S, Lon C, Saunders D, Mohammed R, et al.
N Engl J Med
. 2019 Jan;
380(3):215-228.
PMID: 30650322
Background: Treatment of Plasmodium vivax malaria requires the clearing of asexual parasites, but relapse can be prevented only if dormant hypnozoites are cleared from the liver (a treatment termed "radical...
5.
Green J, Mohamed K, Goyal N, Bouhired S, Hussaini A, Jones S, et al.
Antimicrob Agents Chemother
. 2016 Oct;
60(12):7321-7332.
PMID: 27697758
Tafenoquine is in development as a single-dose treatment for relapse prevention in individuals with Plasmodium vivax malaria. Tafenoquine must be coadministered with a blood schizonticide, either chloroquine or artemisinin-based combination...