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Sinisa Dovat

Explore the profile of Sinisa Dovat including associated specialties, affiliations and a list of published articles. Areas
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Articles 90
Citations 1542
Followers 0
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Recent Articles
1.
Han Q, Gu Y, Xiang H, Zhang L, Wang Y, Yang C, et al.
Blood . 2025 Jan; PMID: 39785511
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy with a poor prognosis and limited options for targeted therapies. Identifying new molecular targets to develop novel therapeutic strategies is...
2.
Golla U, Patel S, Shah N, Talamo S, Bhalodia R, Claxton D, et al.
Cancers (Basel) . 2024 Oct; 16(20). PMID: 39456548
Drug repurposing is a strategy to discover new therapeutic uses for existing drugs, which have well-established toxicity profiles and are often more affordable. This approach has gained significant attention in...
3.
G C B, Hoyt L, Dovat S, Dong F
J Biol Chem . 2024 Oct; 300(11):107860. PMID: 39374784
Gfi1 is a transcriptional repressor that plays a critical role in hematopoiesis. The repressive activity of Gfi1 is mediated mainly by its SNAG domain that interacts with and thereby recruits...
4.
Guo X, Zhang R, Liu J, Li M, Song C, Dovat S, et al.
PLoS One . 2024 Jul; 19(7):e0307986. PMID: 39046969
[This corrects the article DOI: 10.1371/journal.pone.0125429.].
5.
Dovat S, Schramm J
Haematologica . 2024 Jul; 109(12):3835-3837. PMID: 38988268
No abstract available.
6.
Chen W, Williams T, So L, Drew N, Fang J, Ochoa P, et al.
Int J Mol Sci . 2024 Apr; 25(8). PMID: 38673926
Acute myeloid leukemia (AML) is a hematological malignancy that is characterized by an expansion of immature myeloid precursors. Despite therapeutic advances, the prognosis of AML patients remains poor and there...
7.
Dong M, Dharmaraj N, Kaminagakura E, Xue J, Leach D, Hartgerink J, et al.
Biomedicines . 2024 Apr; 12(4). PMID: 38672274
Oral squamous cell carcinoma (OSCC) presents significant treatment challenges due to its poor survival and intense pain at the primary cancer site. Cancer pain is debilitating, contributes to diminished quality...
8.
Budurlean L, Tukaramrao D, Zhang L, Dovat S, Broach J
J Pers Med . 2024 Mar; 14(3). PMID: 38541033
Structural variants drive tumorigenesis by disrupting normal gene function through insertions, inversions, translocations, and copy number changes, including deletions and duplications. Detecting structural variants is crucial for revealing their roles...
9.
Kale V, Hengst J, Sharma A, Golla U, Dovat S, Amin S, et al.
Pharmaceuticals (Basel) . 2023 Aug; 16(8). PMID: 37630974
The Rho associated coiled-coil containing protein kinase (ROCK1 and ROCK2) and myotonic dystrophy-related Cdc-42 binding kinases (MRCKα and MRCKβ) are critical regulators of cell proliferation and cell plasticity, a process...
10.
Elcheva I, Gowda C, Bogush D, Gornostaeva S, Fakhardo A, Sheth N, et al.
Front Immunol . 2023 Jul; 14:1224516. PMID: 37503349
Insulin-like growth factor 2 mRNA-binding proteins (IGF2BP1, IGF2BP2, and IGF2BP3) are a family of RNA-binding proteins that play an essential role in the development and disease by regulating mRNA stability...