Simone Westrom
Overview
Explore the profile of Simone Westrom including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
15
Citations
481
Followers
0
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Related Specialties
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Recent Articles
1.
Yaacov A, Lazarian G, Pandzic T, Westrom S, Baliakas P, Imache S, et al.
Sci Rep
. 2024 Sep;
14(1):21962.
PMID: 39304718
Intratumoral heterogeneity is an important clinical challenge because low burden clones expressing specific genetic alterations drive therapeutic resistance mechanisms. We have developed CAVE (cancer-associated variant enrichment), a gene-agnostic computational tool...
2.
Tobiasson M, Pandzic T, Illman J, Nilsson L, Westrom S, Ejerblad E, et al.
J Clin Oncol
. 2024 Jan;
42(12):1378-1390.
PMID: 38232336
Purpose: Clinical relapse is the major threat for patients with myelodysplastic syndrome (MDS) undergoing hematopoietic stem-cell transplantation (HSCT). Early detection of measurable residual disease (MRD) would enable preemptive treatment and...
3.
Bonfiglio S, Sutton L, Ljungstrom V, Capasso A, Pandzic T, Westrom S, et al.
Blood Adv
. 2023 Jan;
7(12):2794-2806.
PMID: 36696464
Patients with chronic lymphocytic leukemia (CLL) progressing on ibrutinib constitute an unmet need. Though Bruton tyrosine kinase (BTK) and PLCG2 mutations are associated with ibrutinib resistance, their frequency and relevance...
4.
Lampinen M, Hagforsen E, Westrom S, Bergstrom A, Hamberg Levedahl K, Paivandy A, et al.
Exp Dermatol
. 2022 Jul;
31(11):1729-1740.
PMID: 35876458
Mastocytosis is a KIT-related myeloproliferative disease characterised by abnormal expansion of neoplastic mast cells (MC) in the skin or virtually any other organ system. The cutaneous form of adult-onset mastocytosis...
5.
Chen L, Eriksson A, Westrom S, Pandzic T, Lehmann S, Cavelier L, et al.
Nat Commun
. 2022 Jul;
13(1):4033.
PMID: 35821208
Rare tumor-specific mutations in patient samples serve as excellent markers to monitor the course of malignant disease and responses to therapy in clinical routine, and improved assay techniques are needed...
6.
Jadersten M, Boriskina K, Lindholm C, Westrom S, Cavelier L, Hellstrom-Lindberg E, et al.
Leuk Lymphoma
. 2021 Nov;
63(3):755-758.
PMID: 34775885
No abstract available.
7.
Zhang H, Westrom S, Kappelin P, Virtanen M, Vahlquist A, Torma H
Differentiation
. 2021 May;
119:19-27.
PMID: 34029921
A proper skin barrier function requires constant formation of stratum corneum, i.e. the outermost layer of epidermis composed of terminally differentiated keratinocytes. The complex process of converting proliferative basal keratinocytes...
8.
Zhang H, Ericsson M, Westrom S, Vahlquist A, Virtanen M, Torma H
Exp Dermatol
. 2018 Oct;
28(10):1164-1171.
PMID: 30372788
Autosomal recessive congenital ichthyosis (ARCI) is a group of monogenic skin disorders caused by mutations in any of at least 12 different genes, many of which are involved in the...
9.
Zhang H, Ericsson M, Virtanen M, Westrom S, Wahlby C, Vahlquist A, et al.
Exp Dermatol
. 2017 Nov;
27(2):196-199.
PMID: 29094393
Immunofluorescence (IF) and in situ proximity ligation assay (isPLA) are techniques that are used for in situ protein expression and colocalisation analysis, respectively. However, an efficient quantitative method to analyse...
10.
Gordon E, Fukuhara D, Westrom S, Padhan N, Sjostrom E, van Meeteren L, et al.
Sci Signal
. 2016 Jul;
9(437):ra72.
PMID: 27436360
Activation of vascular endothelial growth factor (VEGF) receptor 2 (VEGFR2) by VEGF binding is critical for vascular morphogenesis. In addition, VEGF disrupts the endothelial barrier by triggering the phosphorylation and...