Simone P Sittig
Overview
Explore the profile of Simone P Sittig including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
492
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0
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Recent Articles
1.
Sittig S, van Beek J, Florez-Grau G, Weiden J, Buschow S, van der Net M, et al.
Eur J Immunol
. 2021 Mar;
51(6):1494-1504.
PMID: 33675038
Dendritic cells (DCs) are key regulators of the immune system that shape T cell responses. Regulation of T cell induction by DCs may occur via the intracellular enzyme indoleamine 2,3-dioxygenase...
2.
Skold A, Mathan T, van Beek J, Florez-Grau G, van den Beukel M, Sittig S, et al.
Cancer Immunol Immunother
. 2018 Jul;
67(9):1425-1436.
PMID: 30019146
There has recently been a paradigm shift in the field of dendritic cell (DC)-based immunotherapy, where several clinical studies have confirmed the feasibility and advantageousness of using directly isolated human...
3.
Sittig S, de Vries I, Schreibelt G
Biomedicines
. 2017 May;
3(4):282-303.
PMID: 28536413
Dendritic cell (DC)-based cancer vaccines hold the great promise of tipping the balance from tolerance of the tumor to rejection. In the last two decades, we have gained tremendous knowledge...
4.
Bakdash G, Buschow S, Gorris M, Halilovic A, Hato S, Skold A, et al.
Cancer Res
. 2016 Jun;
76(15):4332-46.
PMID: 27325645
The tumor microenvironment is characterized by regulatory T cells, type II macrophages, myeloid-derived suppressor cells, and other immunosuppressive cells that promote malignant progression. Here we report the identification of a...
5.
Sittig S, Bakdash G, Weiden J, Skold A, Tel J, Figdor C, et al.
Mediators Inflamm
. 2016 Apr;
2016:3605643.
PMID: 27057096
Dendritic cells (DCs) are central players of immune responses; they become activated upon infection or inflammation and migrate to lymph nodes, where they can initiate an antigen-specific immune response by...
6.
Dingjan I, Verboogen D, Paardekooper L, Revelo N, Sittig S, Visser L, et al.
Sci Rep
. 2016 Feb;
6:22064.
PMID: 26907999
Dendritic cells (DCs) present foreign antigen in major histocompatibility complex (MHC) class I molecules to cytotoxic T cells in a process called cross-presentation. An important step in this process is...
7.
Skold A, van Beek J, Sittig S, Bakdash G, Tel J, Schreibelt G, et al.
Cancer Immunol Immunother
. 2015 Aug;
64(11):1461-73.
PMID: 26275446
Dendritic cells (DCs) are key in connecting innate and adaptive immunity. Their potential in inducing specific immune responses has made them interesting targets for immunotherapeutic approaches. Our research group was...
8.
Dorobantu C, Ford-Siltz L, Sittig S, Lanke K, Belov G, van Kuppeveld F, et al.
J Virol
. 2014 Nov;
89(3):1913-8.
PMID: 25410869
PI4KIIIβ recruitment to Golgi membranes relies on GBF1/Arf and ACBD3. Enteroviruses such as poliovirus and coxsackievirus recruit PI4KIIIβ to their replication sites via their 3A proteins. Here, we show that...
9.
Sittig S, Kollgaard T, Gronbaek K, Idorn M, Hennenlotter J, Stenzl A, et al.
Oncoimmunology
. 2013 Nov;
2(9):e26014.
PMID: 24228230
T lymphocytes can mediate the destruction of cancer cells by virtue of their ability to recognize tumor-derived antigenic peptides that are presented on the cell surface in complex with HLA...
10.
Tel J, Sittig S, Blom R, Cruz L, Schreibelt G, Figdor C, et al.
J Immunol
. 2013 Oct;
191(10):5005-12.
PMID: 24127556
Plasmacytoid dendritic cells (pDCs) play a crucial role in initiating immune responses by secreting large amounts of type I IFNs. Currently, the role for human pDCs as professional APCs in...