Ghaith Bakdash
Overview
Explore the profile of Ghaith Bakdash including associated specialties, affiliations and a list of published articles.
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19
Citations
418
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Recent Articles
1.
Schreiber F, Balas I, Robinson M, Bakdash G
Cells
. 2024 Mar;
13(6.
PMID: 38534321
The gut mucosal epithelium is one of the largest organs in the body and plays a critical role in regulating the crosstalk between the resident microbiome and the host. To...
2.
Becker A, Decker A, Florez-Grau G, Bakdash G, Roring R, Stelloo S, et al.
Cell Rep Med
. 2024 Jan;
5(2):101386.
PMID: 38242119
The human dendritic cell (DC) family has recently been expanded by CD1cCD14CD163 DCs, introduced as DC3s. DC3s are found in tumors and peripheral blood of cancer patients. Here, we report...
3.
Villemin C, Six A, Neville B, Lawley T, Robinson M, Bakdash G
Trends Immunol
. 2022 Dec;
44(1):44-59.
PMID: 36464584
The human microbiome is recognized as a key factor in health and disease. This has been further corroborated by identifying changes in microbiome composition and function as a novel hallmark...
4.
Wefers C, Bakdash G, Martin M, Duiveman-de Boer T, Torensma R, Massuger L, et al.
Bio Protoc
. 2021 Sep;
7(7):e2219.
PMID: 34541222
Ovarian cancer is one of the most fatal tumors in women. Due to a lack of symptoms and adequate screening methods, patients are diagnosed at advanced stages with extensive tumor...
5.
Van Ee T, Van Acker H, van Oorschot T, Van Tendeloo V, Smits E, Bakdash G, et al.
Vaccines (Basel)
. 2018 Sep;
6(3).
PMID: 30235890
Dendritic cell (DC) vaccines show promising effects in cancer immunotherapy. However, their efficacy is affected by a number of factors, including (1) the quality of the DC vaccine and (2)...
6.
Skold A, Mathan T, van Beek J, Florez-Grau G, van den Beukel M, Sittig S, et al.
Cancer Immunol Immunother
. 2018 Jul;
67(9):1425-1436.
PMID: 30019146
There has recently been a paradigm shift in the field of dendritic cell (DC)-based immunotherapy, where several clinical studies have confirmed the feasibility and advantageousness of using directly isolated human...
7.
van Beek J, Martens A, Bakdash G, de Vries I
Biomedicines
. 2017 May;
4(1).
PMID: 28536374
Innate lymphoid cells (ILCs) are a group of immune cells of the lymphoid lineage that do not possess antigen specificity. The group includes natural killer (NK) cells, lymphoid tissue inducer...
8.
Mathan T, Textor J, Skold A, Reinieren-Beeren I, van Oorschot T, Bruning M, et al.
Oncotarget
. 2017 Feb;
8(12):19879-19893.
PMID: 28186996
Effective stimulation of immune cells is crucial for the success of cancer immunotherapies. Current approaches to evaluate the efficiency of stimuli are mainly defined by known flow cytometry-based cell activation...
9.
van Beek J, Gorris M, Skold A, Hatipoglu I, Van Acker H, Smits E, et al.
Oncoimmunology
. 2016 Nov;
5(10):e1227902.
PMID: 27853652
Human blood dendritic cells (DCs) hold great potential for use in anticancer immunotherapies. CD1c myeloid DCs and plasmacytoid DCs (pDCs) have been successfully utilized in clinical vaccination trials against melanoma....
10.
Bakdash G, Buschow S, Gorris M, Halilovic A, Hato S, Skold A, et al.
Cancer Res
. 2016 Jun;
76(15):4332-46.
PMID: 27325645
The tumor microenvironment is characterized by regulatory T cells, type II macrophages, myeloid-derived suppressor cells, and other immunosuppressive cells that promote malignant progression. Here we report the identification of a...