» Authors » Simone Keck

Simone Keck

Explore the profile of Simone Keck including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 17
Citations 978
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Moesch M, Usemann J, Bruder E, Romero P, Schwab C, Niesler B, et al.
Eur J Pediatr Surg . 2022 Jul; 33(4):299-309. PMID: 35777734
Objective:  Hirschsprung's disease (HSCR) is a congenital intestinal neurodevelopmental disorder characterized by the absence of enteric ganglion cells in the distal colon. Although Hirschsprung-associated enterocolitis (HAEC) is the most frequent...
2.
Muller I, Kym U, Galati V, Tharakan S, Subotic U, Krebs T, et al.
Front Immunol . 2022 Jan; 12:781147. PMID: 35069554
Infants affected by Hirschsprung disease (HSCR), a neurodevelopmental congenital disorder, lack ganglia of the intrinsic enteric nervous system (aganglionosis) in a variable length of the colon, and are prone to...
3.
Keck S, Galati-Fournier V, Kym U, Moesch M, Usemann J, Muller I, et al.
Cell Mol Gastroenterol Hepatol . 2021 Mar; 12(2):507-545. PMID: 33741501
Background & Aims: Hirschsprung's disease (HSCR) is a congenital intestinal motility disorder defined by the absence of enteric neuronal cells (ganglia) in the distal gut. The development of HSCR-associated enterocolitis...
4.
Cremonesi E, Governa V, Garzon J, Mele V, Amicarella F, Muraro M, et al.
Gut . 2018 Feb; 67(11):1984-1994. PMID: 29437871
Objective: Tumour-infiltrating lymphocytes (TILs) favour survival in human colorectal cancer (CRC). Chemotactic factors underlying their recruitment remain undefined. We investigated chemokines attracting T cells into human CRCs, their cellular sources...
5.
Sucic L, Galati-Fournier V, Kym U, Pfeifle V, Gros S, Schafer K, et al.
Pediatr Allergy Immunol . 2017 Sep; 29(1):104-108. PMID: 28881058
No abstract available.
6.
Pini N, Pfeifle V, Kym U, Keck S, Galati V, Holland-Cunz S, et al.
J Enzyme Inhib Med Chem . 2017 Aug; 32(1):1036-1041. PMID: 28762291
Acute appendicitis is the most common indication for pediatric abdominal emergency surgery. Determination of the severity of appendicitis on clinical grounds is challenging. Complicated appendicitis presenting with perforation, abscess or...
7.
Bosch A, Bolinger B, Keck S, Stepanek O, Ozga A, Galati-Fournier V, et al.
Cell Immunol . 2017 Apr; 316:21-31. PMID: 28366195
While autoimmune T cells are present in most individuals, only a minority of the population suffers from an autoimmune disease. To better appreciate the limits of T cell tolerance, we...
8.
Keck S, Schmaler M, Ganter S, Wyss L, Oberle S, Huseby E, et al.
Proc Natl Acad Sci U S A . 2014 Oct; 111(41):14852-7. PMID: 25267612
Cumulative T-cell receptor signal strength and ensuing T-cell responses are affected by both antigen affinity and antigen dose. Here we examined the distinct contributions of these parameters to CD4 T-cell...
9.
Vukcevic M, Zorzato F, Keck S, Tsakiris D, Keiser J, Maizels R, et al.
J Cell Sci . 2013 May; 126(Pt 15):3485-92. PMID: 23704352
Mutations in RYR1, the gene encoding ryanodine receptor 1, are linked to a variety of neuromuscular disorders including malignant hyperthermia (MH), a pharmacogenetic hypermetabolic disease caused by dysregulation of Ca(2+)...
10.
Keck S, Muller I, Fejer G, Savic I, Tchaptchet S, Nielsen P, et al.
J Immunol . 2011 Mar; 186(9):5478-88. PMID: 21441453
In macrophages, two signaling pathways, dependent on MyD88 or TIR domain-containing adaptor-inducing IFN-β (TRIF) signaling, emanate from the LPS receptor TLR4/MD-2. In this study, we show that in murine bone...