Simone Haeberlein
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Explore the profile of Simone Haeberlein including associated specialties, affiliations and a list of published articles.
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40
Citations
395
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Recent Articles
1.
Fischer-Carvalho A, Taveira-Barbosa T, Verjovski-Almeida S, Haeberlein S, Sena Amaral M
Microorganisms
. 2025 Feb;
13(2).
PMID: 40005763
Schistosomiasis is a neglected tropical disease that affects over 240 million people worldwide. Currently, praziquantel is the only drug recommended by the World Health Organization for treatment. However, cases of...
2.
Moreira B, Gava S, Haeberlein S, Gueye S, Santos E, Weber M, et al.
Front Parasitol
. 2025 Jan;
3():1394407.
PMID: 39817168
Introduction: Schistosomiasis has for many years relied on a single drug, praziquantel (PZQ) for treatment of the disease. Immense efforts have been invested in the discovery of protein kinase (PK)...
3.
Kirchner M, Marner M, Kramer T, Muhlemeyer F, Eichberg J, Oberpaul M, et al.
RSC Adv
. 2025 Jan;
15(2):824-831.
PMID: 39802477
Parasites account for huge economic losses by infecting agriculturally important plants and animals. Furthermore, morbidity and death caused by parasites affect a large part of the world population, especially in...
4.
Moescheid M, Lu Z, Soria C, Quack T, Puckelwaldt O, Holroyd N, et al.
Nucleic Acids Res
. 2024 Dec;
53(4).
PMID: 39676663
Studies on transcription regulation in platyhelminth development are scarce, especially for parasitic flatworms. Here, we employed single-cell transcriptomics to identify genes involved in reproductive development in the trematode model Schistosoma...
5.
Luh D, Ghezellou P, Heiles S, Gramberg S, Haeberlein S, Spengler B
ACS Infect Dis
. 2024 Nov;
10(12):4233-4245.
PMID: 39510517
Fascioliasis, a zoonotic disease caused by liver flukes of the genus , poses significant health threats to both humans and livestock. While some infections remain asymptomatic, others can lead to...
6.
Gramberg S, Puckelwaldt O, Schmitt T, Lu Z, Haeberlein S
Nat Commun
. 2024 Oct;
15(1):8918.
PMID: 39414795
The spatial organization of gene expression dictates tissue functions in multicellular parasites. Here, we present the spatial transcriptome of a parasitic flatworm, the common liver fluke Fasciola hepatica. We identify...
7.
Muller H, Strassmann J, Baier A, von Bulow V, Stettler F, Hagen M, et al.
Cells
. 2024 Oct;
13(19.
PMID: 39404406
Schistosomiasis affects over 250 million people worldwide, with the highest prevalence at the age of 10-14 years. The influence of the host's age on the severity of liver damage is...
8.
Sprague D, Park S, Gramberg S, Bauer L, Rohr C, Chulkov E, et al.
Nat Struct Mol Biol
. 2024 May;
31(9):1386-1393.
PMID: 38714890
Diseases caused by parasitic flatworms impart a considerable healthcare burden worldwide. Many of these diseases-for example, the parasitic blood fluke infection schistosomiasis-are treated with the drug praziquantel (PZQ). However, PZQ...
9.
Harle L, von Bulow V, Knedla L, Stettler F, Muller H, Zahner D, et al.
Sci Rep
. 2023 Nov;
13(1):20390.
PMID: 37990129
Schistosomiasis is a parasitic disease affecting more than 250 million people worldwide. The transcription factor c-Jun, which is induced in S. mansoni infection-associated liver disease, can promote hepatocyte survival but...
10.
Sprague D, Park S, Gramberg S, Bauer L, Rohr C, Chulkov E, et al.
bioRxiv
. 2023 Oct;
PMID: 37790347
Diseases caused by parasitic flatworms impart a considerable healthcare burden worldwide. Many of these diseases - for example, the parasitic blood fluke infection, schistosomiasis - are treated with the drug...