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Simona Marchitti

Explore the profile of Simona Marchitti including associated specialties, affiliations and a list of published articles. Areas
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Articles 57
Citations 702
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Recent Articles
1.
Forte M, Marchitti S, di Nonno F, Pietrangelo D, Stanzione R, Cotugno M, et al.
Biochim Biophys Acta Mol Cell Res . 2024 Oct; 1872(1):119860. PMID: 39383950
Atrial natriuretic peptide (ANP), a cardiac hormone involved in the regulation of water/sodium balance and blood pressure, is also secreted by endothelial cells, where it exerts protective effects in response...
2.
Schirone L, Vecchio D, Valenti V, Forte M, Relucenti M, Angelini A, et al.
Cell Mol Life Sci . 2023 Aug; 80(9):245. PMID: 37566283
Heart failure is a major side effect of doxorubicin (DOX) treatment in patients with cancer. However, the mechanisms underlying the development of DOX-induced heart failure need to be addressed. This...
3.
Gallo G, Forte M, Cotugno M, Marchitti S, Stanzione R, Tocci G, et al.
Mol Med . 2023 Aug; 29(1):107. PMID: 37558995
Background: A dysfunction of NADH dehydrogenase, the mitochondrial Complex I (CI), associated with the development of left ventricular hypertrophy (LVH) in previous experimental studies. A deficiency of Ndufc2 (subunit of...
4.
Busceti C, Carrizzo A, Bianchi F, De Lucia M, Damato A, Cazzin C, et al.
Circ Res . 2023 May; 132(11):1489-1504. PMID: 37144413
Background: Dkk3 (Dickkopf-3) is a secreted glycoprotein known for its proapoptotic and angiogenic activity. The role of Dkk3 in cardiovascular homeostasis is largely unknown. Remarkably, the gene maps within a...
5.
Raffa S, Forte M, Gallo G, Ranieri D, Marchitti S, Magri D, et al.
Cell Mol Life Sci . 2023 Apr; 80(5):134. PMID: 37099206
Mitochondrial dysfunction, causing increased reactive oxygen species (ROS) production, is a molecular feature of heart failure (HF). A defective antioxidant response and mitophagic flux were reported in circulating leucocytes of...
6.
Stanzione R, Forte M, Cotugno M, Oppedisano F, Carresi C, Marchitti S, et al.
Nutrients . 2023 Mar; 15(6). PMID: 36986064
High salt load is a known noxious stimulus for vascular cells and a risk factor for cardiovascular diseases in both animal models and humans. The stroke-prone spontaneously hypertensive rat (SHRSP)...
7.
Grimaldi M, Rosato E, DAngelo A, Cristiano E, Marchitti S, Volpe M, et al.
Front Cardiovasc Med . 2023 Feb; 9:1021048. PMID: 36733829
Background: The tricuspid annular plane systolic excursion/systolic pulmonary arterial pressure (TAPSE/sPAP) ratio is an echocardiographic estimation of the right ventricle to pulmonary artery (RV/PA) coupling, with a validated prognostic role...
8.
Martinelli O, Peruzzi M, Bartimoccia S, DAmico A, Marchitti S, Rubattu S, et al.
Antioxidants (Basel) . 2022 Sep; 11(9). PMID: 36139910
Trehalose, spermidine, nicotinamide, and polyphenols have been shown to display pro-autophagic and antioxidant properties, eventually reducing cardiovascular and ischemic complications. This study aimed to investigate whether a mixture of these...
9.
Forte M, Marchitti S, di Nonno F, Stanzione R, Schirone L, Cotugno M, et al.
Autophagy . 2022 Aug; 19(4):1087-1099. PMID: 35998113
NPPA/atrial natriuretic peptide (natriuretic peptide type A) exerts critical pleiotropic effects in the cardiovascular system, limiting cardiomyocyte hypertrophy and death, reducing cardiac fibrosis and promoting vascular integrity. However, the molecular...
10.
Gallo G, Migliarino S, Cotugno M, Stanzione R, Burocchi S, Bianchi F, et al.
Front Cardiovasc Med . 2022 Jun; 9:921244. PMID: 35711349
Background: Among several potential mechanisms, mitochondrial dysfunction has been proposed to be involved in the pathogenesis of coronary artery disease (CAD). A mitochondrial complex I deficiency severely impairs cardiovascular health...