Franca Bianchi
Overview
Explore the profile of Franca Bianchi including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
658
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Recent Articles
1.
Gallo G, Forte M, Cotugno M, Marchitti S, Stanzione R, Tocci G, et al.
Mol Med
. 2023 Aug;
29(1):107.
PMID: 37558995
Background: A dysfunction of NADH dehydrogenase, the mitochondrial Complex I (CI), associated with the development of left ventricular hypertrophy (LVH) in previous experimental studies. A deficiency of Ndufc2 (subunit of...
2.
Busceti C, Carrizzo A, Bianchi F, De Lucia M, Damato A, Cazzin C, et al.
Circ Res
. 2023 May;
132(11):1489-1504.
PMID: 37144413
Background: Dkk3 (Dickkopf-3) is a secreted glycoprotein known for its proapoptotic and angiogenic activity. The role of Dkk3 in cardiovascular homeostasis is largely unknown. Remarkably, the gene maps within a...
3.
Raffa S, Forte M, Gallo G, Ranieri D, Marchitti S, Magri D, et al.
Cell Mol Life Sci
. 2023 Apr;
80(5):134.
PMID: 37099206
Mitochondrial dysfunction, causing increased reactive oxygen species (ROS) production, is a molecular feature of heart failure (HF). A defective antioxidant response and mitophagic flux were reported in circulating leucocytes of...
4.
Algieri C, Bernardini C, Marchi S, Forte M, Tallarida M, Bianchi F, et al.
Pharmacol Res
. 2022 Nov;
187:106561.
PMID: 36410676
The compromised viability and function of cardiovascular cells are rescued by small molecules of triazole derivatives (Tzs), identified as 3a and 3b, by preventing mitochondrial dysfunction. The oxidative phosphorylation improves...
5.
Forte M, Marchitti S, di Nonno F, Stanzione R, Schirone L, Cotugno M, et al.
Autophagy
. 2022 Aug;
19(4):1087-1099.
PMID: 35998113
NPPA/atrial natriuretic peptide (natriuretic peptide type A) exerts critical pleiotropic effects in the cardiovascular system, limiting cardiomyocyte hypertrophy and death, reducing cardiac fibrosis and promoting vascular integrity. However, the molecular...
6.
Gallo G, Migliarino S, Cotugno M, Stanzione R, Burocchi S, Bianchi F, et al.
Front Cardiovasc Med
. 2022 Jun;
9:921244.
PMID: 35711349
Background: Among several potential mechanisms, mitochondrial dysfunction has been proposed to be involved in the pathogenesis of coronary artery disease (CAD). A mitochondrial complex I deficiency severely impairs cardiovascular health...
7.
Stanzione R, Cotugno M, Forte M, Bianchi F, Marchitti S, Palomba N, et al.
Life (Basel)
. 2022 May;
12(5).
PMID: 35629388
The mitochondrial uncoupling protein 2 (UCP2) acts as an anion transporter and as an antioxidant factor able to reduce the reactive oxygen species level. Based on its effects, UCP2 prevents...
8.
Stanzione R, Forte M, Cotugno M, Bianchi F, Marchitti S, Rubattu S
Pflugers Arch
. 2021 Nov;
474(1):141-153.
PMID: 34757454
Stroke represents a main cause of death and permanent disability worldwide. In the attempt to develop targeted preventive and therapeutic strategies, several efforts were performed over the last decades to...
9.
Forte M, Bianchi F, Cotugno M, Marchitti S, Stanzione R, Maglione V, et al.
Cell Death Dis
. 2021 Oct;
12(10):919.
PMID: 34625529
The mitochondrial uncoupling protein 2 (UCP2) plays a protective function in the vascular disease of both animal models and humans. UCP2 downregulation upon high-salt feeding favors vascular dysfunction in knock-out...
10.
Forte M, Marchitti S, Cotugno M, di Nonno F, Stanzione R, Bianchi F, et al.
Pharmacol Res
. 2021 Sep;
173:105875.
PMID: 34500062
Cerebrovascular disease, a frequent complication of hypertension, is a major public health issue for which novel therapeutic and preventive approaches are needed. Autophagy activation is emerging as a potential therapeutic...