Simona Baghai Sain
Overview
Explore the profile of Simona Baghai Sain including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
125
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0
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Recent Articles
1.
Renz P, Ghoshdastider U, Baghai Sain S, Valdivia-Francia F, Khandekar A, Ormiston M, et al.
Nature
. 2024 Jul;
632(8024):419-428.
PMID: 39020166
The tumour evolution model posits that malignant transformation is preceded by randomly distributed driver mutations in cancer genes, which cause clonal expansions in phenotypically normal tissues. Although clonal expansions can...
2.
Lafzi A, Borrelli C, Baghai Sain S, Bach K, Kretz J, Handler K, et al.
Mol Syst Biol
. 2024 Jan;
20(2):98-119.
PMID: 38225383
Sequencing-based spatial transcriptomics (ST) methods allow unbiased capturing of RNA molecules at barcoded spots, charting the distribution and localization of cell types and transcripts across a tissue. While the coarse...
3.
Tomaiuolo P, Piras I, Baghai Sain S, Picinelli C, Baccarin M, Castronovo P, et al.
Sci Rep
. 2023 Jan;
13(1):807.
PMID: 36646776
Autism spectrum disorder (ASD) is a neurodevelopmental condition with onset in early childhood, still diagnosed only through clinical observation due to the lack of laboratory biomarkers. Early detection strategies would...
4.
Mikl M, Eletto D, Nijim M, Lee M, Lafzi A, Mhamedi F, et al.
Nucleic Acids Res
. 2022 Sep;
50(18):10643-10664.
PMID: 36156153
Asymmetric subcellular mRNA localization allows spatial regulation of gene expression and functional compartmentalization. In neurons, localization of specific mRNAs to neurites is essential for cellular functioning. However, it is largely...
5.
Lenti E, Genovese L, Bianchessi S, Maurizio A, Baghai Sain S, di Lillo A, et al.
Immunity
. 2022 Mar;
55(4):606-622.e6.
PMID: 35358427
Lymph node (LN) stromal cells play a crucial role in LN development and in supporting adaptive immune responses. However, their origin, differentiation pathways, and transcriptional programs are still elusive. Here,...
6.
Adamo S, Michler J, Zurbuchen Y, Cervia C, Taeschler P, Raeber M, et al.
Nature
. 2021 Dec;
602(7895):148-155.
PMID: 34875673
Immunological memory is a hallmark of adaptive immunity and facilitates an accelerated and enhanced immune response upon re-infection with the same pathogen. Since the outbreak of the ongoing COVID-19 pandemic,...
7.
Voellenkle C, Perfetti A, Carrara M, Fuschi P, Renna L, Longo M, et al.
Int J Mol Sci
. 2019 Apr;
20(8).
PMID: 31010208
Circular RNAs (circRNAs) constitute a recently re-discovered class of non-coding RNAs functioning as sponges for miRNAs and proteins, affecting RNA splicing and regulating transcription. CircRNAs are generated by "back-splicing", which...
8.
Dumitru M, Mohammad-Djafari A, Baghai Sain S
EURASIP J Bioinform Syst Biol
. 2016 Feb;
2016(1):3.
PMID: 26834783
The toxicity and efficacy of more than 30 anticancer agents present very high variations, depending on the dosing time. Therefore, the biologists studying the circadian rhythm require a very precise...