Simon Thebault
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Explore the profile of Simon Thebault including associated specialties, affiliations and a list of published articles.
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32
Citations
346
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Recent Articles
1.
Espinoza D, Zrzavy T, Breville G, Thebault S, Marefi A, Mexhitaj I, et al.
bioRxiv
. 2025 Mar;
PMID: 40060552
The cerebrospinal fluid (CSF) provides a unique glimpse into the central nervous system (CNS) compartment and offers insights into immune processes associated with both healthy immune surveillance as well as...
2.
Reilly A, Beauvais A, Al-Aarg M, Yaworski R, Sutton E, Thebault S, et al.
J Neuromuscul Dis
. 2025 Feb;
11(6):1200-1210.
PMID: 39973467
Background: Spinal Muscular Atrophy (SMA) is an inherited neurodegenerative disease caused by the loss or mutation of the survival motor neuron 1 ) gene. Though classically regarded as a motor...
3.
Thebault S, Fereshtehnejad S, Bergman H, Breville G, Abdoli M, Booth R, et al.
Sci Rep
. 2024 Nov;
14(1):29135.
PMID: 39587121
Our objective was to evaluate the individual and combined prognostic attributes of baseline serum and CSF measurements of Neurofilament light chain (sNfL, cNfL) and glial fibrillary acidic protein (sGFAP, cGFAP)...
4.
Hamwi M, Thebault S, Melkus G, Auriat A, Pham A, Carrington A, et al.
Mult Scler Relat Disord
. 2024 Nov;
80:105066.
PMID: 39491411
Purpose: We sought to determine if structural network parameters add to traditional markers of MS treatment response following immunoablation and autologous haemopoietic stem cell transplantation (IAHSCT). The post-IAHSCT paradigm afforded...
5.
Wurtz L, Knyazhanskaya E, Sohaei D, Prassas I, Pittock S, Willrich M, et al.
Clin Proteomics
. 2024 Jun;
21(1):42.
PMID: 38880880
Background: Multiple sclerosis (MS) is a clinically and biologically heterogenous disease with currently unpredictable progression and relapse. After the development and success of neurofilament as a cerebrospinal fluid (CSF) biomarker,...
6.
Soldan S, Su C, Monaco M, Yoon L, Kannan T, Zankharia U, et al.
Nat Microbiol
. 2024 May;
9(6):1540-1554.
PMID: 38806670
Epstein-Barr virus (EBV) is an aetiologic risk factor for the development of multiple sclerosis (MS). However, the role of EBV-infected B cells in the immunopathology of MS is not well...
7.
Khalil M, Teunissen C, Lehmann S, Otto M, Piehl F, Ziemssen T, et al.
Nat Rev Neurol
. 2024 Apr;
20(5):269-287.
PMID: 38609644
Neurofilament proteins have been validated as specific body fluid biomarkers of neuro-axonal injury. The advent of highly sensitive analytical platforms that enable reliable quantification of neurofilaments in blood samples and...
8.
Cross A, Gelfand J, Thebault S, Bennett J, von Budingen H, Cameron B, et al.
JAMA Neurol
. 2024 Mar;
PMID: 38466277
Importance: Biomarkers distinguishing nonrelapsing progressive disease biology from relapsing biology in multiple sclerosis (MS) are lacking. Cerebrospinal fluid (CSF) is an accessible fluid that most closely reflects central nervous system...
9.
Wilson D, Chan D, Chang L, Mathis R, Verberk I, Montalban X, et al.
Clin Chem Lab Med
. 2023 Sep;
62(2):322-331.
PMID: 37702323
Objectives: Neurofilament light chain (NfL) has emerged as a promising biomarker for detecting and monitoring axonal injury. Until recently, NfL could only be reliably measured in cerebrospinal fluid, but digital...
10.
Sohaei D, Thebault S, Avery L, Batruch I, Lam B, Xu W, et al.
Clin Proteomics
. 2023 Aug;
20(1):33.
PMID: 37644477
Background: Multiple sclerosis (MS) remains a highly unpredictable disease. Many hope that fluid biomarkers may contribute to better stratification of disease, aiding the personalisation of treatment decisions, ultimately improving patient...