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Simon OShaughnessy

Explore the profile of Simon OShaughnessy including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 33
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Recent Articles
1.
OShaughnessy S, Finlay D
Immunometabolism (Cobham) . 2024 Nov; 6(4):e00049. PMID: 39544255
A recent paper published in in August 2024 by Dirk Brenner's laboratory highlights the importance of effectively managing reactive oxygen species (ROS) in gut T17 T cells for minimizing the...
2.
Ryan E, Clutter C, De Barra C, Jenkins B, OShaughnessy S, Ryan O, et al.
J Immunol . 2024 Apr; 212(11):1706-1713. PMID: 38619286
Mucosal-Associated Invariant T (MAIT) cells are a population of innate T cells that play a critical role in host protection against bacterial and viral pathogens. Upon activation, MAIT cells can...
3.
Pelgrom L, Davis G, OShaughnessy S, Wezenberg E, van Kasteren S, Finlay D, et al.
Cell Rep . 2023 Jul; 42(8):112828. PMID: 37478011
System-level analysis of single-cell data is rapidly transforming the field of immunometabolism. Given the competitive demand for nutrients in immune microenvironments, there is a need to understand how and when...
4.
Littwitz-Salomon E, Moreira D, Frost J, Choi C, Liou K, Ahern D, et al.
Nat Commun . 2021 Sep; 12(1):5376. PMID: 34508086
Natural killer (NK) cells are important early responders against viral infections. Changes in metabolism are crucial to fuel NK cell responses, and altered metabolism is linked to NK cell dysfunction...