Simon Merkt
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Explore the profile of Simon Merkt including associated specialties, affiliations and a list of published articles.
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7
Citations
85
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Recent Articles
1.
Gudina E, Elsbernd K, Yilma D, Kisch R, Wallrafen-Sam K, Abebe G, et al.
Vaccines (Basel)
. 2024 Jul;
12(7).
PMID: 39066383
This study aimed to retrospectively assess the cost-effectiveness of various COVID-19 vaccination strategies in Ethiopia. It involved healthcare workers (HCWs) and community participants; and was conducted through interviews and serological...
2.
Merkt S, Ali S, Gudina E, Adissu W, Gize A, Muenchhoff M, et al.
Nat Commun
. 2024 Apr;
15(1):3463.
PMID: 38658564
Under-reporting of COVID-19 and the limited information about circulating SARS-CoV-2 variants remain major challenges for many African countries. We analyzed SARS-CoV-2 infection dynamics in Addis Ababa and Jimma, Ethiopia, focusing...
3.
Schalte Y, Frohlich F, Jost P, Vanhoefer J, Pathirana D, Stapor P, et al.
Bioinformatics
. 2023 Nov;
39(11).
PMID: 37995297
Summary: Mechanistic models are important tools to describe and understand biological processes. However, they typically rely on unknown parameters, the estimation of which can be challenging for large and complex...
4.
Stapor P, Schmiester L, Wierling C, Merkt S, Pathirana D, Lange B, et al.
Nat Commun
. 2022 Jan;
13(1):34.
PMID: 35013141
Quantitative dynamic models are widely used to study cellular signal processing. A critical step in modelling is the estimation of unknown model parameters from experimental data. As model sizes and...
5.
Gudina E, Ali S, Girma E, Gize A, Tegene B, Hundie G, et al.
Lancet Glob Health
. 2021 Oct;
9(11):e1517-e1527.
PMID: 34678196
Background: Over 1 year since the first reported case, the true COVID-19 burden in Ethiopia remains unknown due to insufficient surveillance. We aimed to investigate the seroepidemiology of SARS-CoV-2 among...
6.
Raimundez E, Dudkin E, Vanhoefer J, Alamoudi E, Merkt S, Fuhrmann L, et al.
Epidemics
. 2021 Feb;
34:100439.
PMID: 33556763
Epidemiological models are widely used to analyze the spread of diseases such as the global COVID-19 pandemic caused by SARS-CoV-2. However, all models are based on simplifying assumptions and often...
7.
Schmiester L, Schalte Y, Bergmann F, Camba T, Dudkin E, Egert J, et al.
PLoS Comput Biol
. 2021 Jan;
17(1):e1008646.
PMID: 33497393
Reproducibility and reusability of the results of data-based modeling studies are essential. Yet, there has been-so far-no broadly supported format for the specification of parameter estimation problems in systems biology....