Simon Mantha
Overview
Explore the profile of Simon Mantha including associated specialties, affiliations and a list of published articles.
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39
Citations
836
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Recent Articles
1.
Patell R, Zwicker J, Singh R, Mantha S
Bleeding Thromb Vasc Biol
. 2024 Sep;
3(Suppl 1).
PMID: 39323613
The goal of machine learning (ML) is to create informative signals and useful tasks by leveraging large datasets to derive computational algorithms. ML has the potential to revolutionize the healthcare...
2.
Streiff M, Holmstrom B, Angelini D, Ashrani A, Buckner T, Diep R, et al.
J Natl Compr Canc Netw
. 2024 Sep;
22(7):483-506.
PMID: 39236759
The NCCN Guidelines for Cancer-Associated Venous Thromboembolic Disease provide strategies for the prevention, diagnosis, and treatment of venous thromboembolism (VTE) in adult patients with cancer. VTE is a common and...
3.
Jee J, Brannon A, Singh R, Derkach A, Fong C, Lee A, et al.
Nat Med
. 2024 Aug;
30(9):2499-2507.
PMID: 39147831
Cancer-associated venous thromboembolism (VTE) is a major source of oncologic cost, morbidity and mortality. Identifying high-risk patients for prophylactic anticoagulation is challenging and adds to clinician burden. Circulating tumor DNA...
4.
Moufarrij S, OCearbhaill R, Zhou Q, Iasonos A, Mantha S, Zwicker J, et al.
Gynecol Oncol Rep
. 2024 May;
53:101399.
PMID: 38757118
Objective: Romiplostim is used to treat chemotherapy-induced thrombocytopenia in a variety of tumor types; however, few studies have examined its use in breast and gynecologic cancers. We evaluated platelet response...
5.
Lam B, Chrysafi P, Chiasakul T, Khosla H, Karagkouni D, McNichol M, et al.
Blood Adv
. 2024 Mar;
8(12):2991-3000.
PMID: 38522096
Venous thromboembolism (VTE) is a leading cause of preventable in-hospital mortality. Monitoring VTE cases is limited by the challenges of manual medical record review and diagnosis code interpretation. Natural language...
6.
Krystel-Whittemore M, Petrova-Drus K, Ptashkin R, Ewalt M, Yao J, Liu Y, et al.
Haematologica
. 2024 Mar;
109(10):3269-3281.
PMID: 38450530
Comprehensive genomic sequencing is becoming a critical component in the assessment of hematologic malignancies, with broad implications for patients' management. In this context, unequivocally discriminating somatic from germline events is...
7.
Stonestrom A, Menghrajani K, Devlin S, Franch-Exposito S, Ptashkin R, Patel S, et al.
Blood Adv
. 2023 Dec;
8(4):846-856.
PMID: 38147626
Clonal hematopoiesis (CH) identified by somatic gene variants with variant allele fraction (VAF) ≥ 2% is associated with an increased risk of hematologic malignancy. However, CH defined by a broader...
8.
Mantha S, Chatterjee S, Singh R, Cadley J, Poon C, Chatterjee A, et al.
Res Sq
. 2023 May;
PMID: 37214902
Venous thromboembolism (VTE) is a common and impactful complication of cancer. Several clinical prediction rules have been devised to estimate the risk of a thrombotic event in this patient population,...
9.
Tumor Genomic Profile Is Associated With Arterial Thromboembolism Risk in Patients With Solid Cancer
Feldman S, Gupta D, Navi B, Grace Ho K, Willeit P, Devlin S, et al.
JACC CardioOncol
. 2023 May;
5(2):246-255.
PMID: 37144118
Background: Patients with cancer have an increased risk for arterial thromboembolism (ATE). Scant data exist about the impact of cancer-specific genomic alterations on the risk for ATE. Objectives: The aim...
10.
Mantha S, Rak J
Thromb Res
. 2022 Oct;
213 Suppl 1:S29-S34.
PMID: 36210557
Cancer has long been known to incur an increased risk of venous thromboembolism (VTE). Multiple risk factors for cancer-associated thrombosis (CAT) have been identified, and several pathophysiological mechanisms elucidated. However,...