Simon M Lin
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Explore the profile of Simon M Lin including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Rastegar-Mojarad M, Ye Z, Kolesar J, Hebbring S, Lin S
Nat Biotechnol
. 2015 Apr;
33(4):342-5.
PMID: 25850054
No abstract available.
12.
He M, Person T, Hebbring S, Heinzen E, Ye Z, Schrodi S, et al.
J Med Genet
. 2015 Jan;
52(4):282-8.
PMID: 25587064
Background: Whole-genome sequencing (WGS) and whole-exome sequencing (WES) technologies are increasingly used to identify disease-contributing mutations in human genomic studies. It can be a significant challenge to process such data,...
13.
Munro S, Lund S, Pine P, Binder H, Clevert D, Conesa A, et al.
Nat Commun
. 2014 Sep;
5:5125.
PMID: 25254650
There is a critical need for standard approaches to assess, report and compare the technical performance of genome-scale differential gene expression experiments. Here we assess technical performance with a proposed...
14.
Wall D, Ray W, Pathak R, Lin S
J Diabetes Sci Technol
. 2014 Jul;
8(6):1245-6.
PMID: 25015954
No abstract available.
15.
Sun X, Lin S, Yan X
Biomed Res Int
. 2014 Jul;
2014:736798.
PMID: 24995327
NAGNAG alternative splicing plays an essential role in biological processes and represents a highly adaptable system for posttranslational regulation of gene function. NAGNAG alternative splicing impacts a myriad of biological...
16.
Chute C, Ullman-Cullere M, Wood G, Lin S, He M, Pathak J
Genet Med
. 2013 Sep;
15(10):802-9.
PMID: 24008998
Health care has become increasingly information intensive. The advent of genomic data, integrated into patient care, significantly accelerates the complexity and amount of clinical data. Translational research in the present...
17.
Xu W, Wang H, Cheng W, Fu D, Xia T, Kibbe W, et al.
PLoS One
. 2012 Dec;
7(12):e49686.
PMID: 23251346
Identification of gene-disease association is crucial to understanding disease mechanism. A rapid increase in biomedical literatures, led by advances of genome-scale technologies, poses challenge for manually-curated-based annotation databases to characterize...
18.
Peng K, Xu W, Zheng J, Huang K, Wang H, Tong J, et al.
Nucleic Acids Res
. 2012 Dec;
41(Database issue):D553-60.
PMID: 23197658
Disease and Gene Annotations database (DGA, http://dga.nubic.northwestern.edu) is a collaborative effort aiming to provide a comprehensive and integrative annotation of the human genes in disease network context by integrating computable...
19.
Jiang H, An L, Lin S, Feng G, Qiu Y
PLoS One
. 2012 Oct;
7(10):e46450.
PMID: 23049702
The advent of next-generation sequencing technologies has greatly promoted the field of metagenomics which studies genetic material recovered directly from an environment. Characterization of genomic composition of a metagenomic sample...
20.
Hong H, Xu L, Liu J, Jones W, Su Z, Ning B, et al.
PLoS One
. 2012 Sep;
7(9):e44483.
PMID: 22970228
During the last several years, high-density genotyping SNP arrays have facilitated genome-wide association studies (GWAS) that successfully identified common genetic variants associated with a variety of phenotypes. However, each of...