Simon M L Paine
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Explore the profile of Simon M L Paine including associated specialties, affiliations and a list of published articles.
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23
Citations
327
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Recent Articles
1.
Schmid S, Mirchia K, Tietze A, Liu I, Siewert C, Nuckles J, et al.
Neuro Oncol
. 2024 Dec;
PMID: 39713960
Background: Intracerebral schwannomas are rare tumors resembling their peripheral nerve sheath counterparts but localized in the CNS. They are not classified as a separate tumor type in the 2021 WHO...
2.
Turner J, Bruels C, Daugherty A, Estrella E, Stafki S, Syeda S, et al.
Muscle Nerve
. 2024 Jul;
70(4):843-850.
PMID: 39072769
Introduction/aims: Heterogeneous nuclear ribonucleoprotein A1 is involved in nucleic acid homeostatic functions. The encoding gene HNRNPA1 has been associated with several neuromuscular disorders including an amyotrophic lateral sclerosis-like phenotype, distal...
3.
Griesinger A, Riemondy K, Eswaran N, Donson A, Willard N, Prince E, et al.
iScience
. 2023 Sep;
26(9):107585.
PMID: 37694144
Ependymoma (EPN) is a devastating childhood brain tumor. Single-cell analyses have illustrated the cellular heterogeneity of EPN tumors, identifying multiple neoplastic cell states including a mesenchymal-differentiated subpopulation which characterizes the...
4.
Andrieux G, Das T, Griffin M, Straehle J, Paine S, Beck J, et al.
Genome Med
. 2023 Jul;
15(1):48.
PMID: 37434262
Background: Spatiotemporal heterogeneity originating from genomic and transcriptional variation was found to contribute to subtype switching in isocitrate dehydrogenase-1 wild-type glioblastoma (GBM) prior to and upon recurrence. Fluorescence-guided neurosurgical resection...
5.
Deacon S, Dalleywater W, Peat C, Paine S, Dineen R
Cerebellum
. 2023 Apr;
23(2):502-511.
PMID: 37120494
Cerebellar neurodegeneration is a classical feature of ataxia telangiectasia (A-T), an autosomal recessive condition caused by loss-of-function mutation of the ATM gene, a gene with multiple regulatory functions. The increased...
6.
He W, Edney M, Paine S, Griffiths R, Scurr D, Rahman R, et al.
Anal Chem
. 2023 Mar;
95(14):5994-6001.
PMID: 36995369
Glioblastoma (GBM) is an incurable brain cancer with a median survival of less than two years from diagnosis. The standard treatment of GBM is multimodality therapy comprising surgical resection, radiation,...
7.
Chapman R, Ghasemi D, Andreiuolo F, Zschernack V, Tauziede Espariat A, Buttarelli F, et al.
Neuro Oncol
. 2023 Mar;
25(10):1871-1882.
PMID: 36916248
Background: Accurate identification of brain tumor molecular subgroups is increasingly important. We aimed to establish the most accurate and reproducible ependymoma subgroup biomarker detection techniques, across 147 cases from International...
8.
Ritzmann T, Chapman R, Kilday J, Thorp N, Modena P, Dineen R, et al.
Neuro Oncol
. 2022 Jan;
24(6):936-948.
PMID: 35018471
Background: SIOP Ependymoma I was a non-randomised trial assessing event free and overall survival (EFS/OS) of non-metastatic intracranial ependymoma in children aged 3-21 years treated with a staged management strategy....
9.
Ritzmann T, Rogers H, Paine S, Storer L, Jacques T, Chapman R, et al.
Pediatr Blood Cancer
. 2020 Jul;
67(9):e28426.
PMID: 32614133
Background: Relapse occurs in 50% of pediatric ependymoma cases and has poor prognosis. Few studies have investigated the clinical progress of relapsed disease, and treatment lacks a standardized approach. Methods...
10.
Bennett C, Kohe S, Gill S, Davies N, Wilson M, Storer L, et al.
Sci Rep
. 2018 Aug;
8(1):11992.
PMID: 30097636
Paediatric brain tumors are becoming well characterized due to large genomic and epigenomic studies. Metabolomics is a powerful analytical approach aiding in the characterization of tumors. This study shows that...