Simon J Dowell
Overview
Explore the profile of Simon J Dowell including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
24
Citations
1397
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Philippe A, Kleinau G, Gruner J, Wu S, Postpieszala D, Speck D, et al.
Int J Mol Sci
. 2022 Apr;
23(7).
PMID: 35409344
The angiotensin II (Ang II) type 1 receptor (ATR) is involved in the regulation of blood pressure (through vasoconstriction) and water and ion homeostasis (mediated by interaction with the endogenous...
2.
Knight A, Hemmings J, Winfield I, Leuenberger M, Frattini E, Frenguelli B, et al.
J Med Chem
. 2020 Sep;
63(18):10531.
PMID: 32870678
No abstract available.
3.
Bhudia N, Desai S, King N, Ancellin N, Grillot D, Barnes A, et al.
Sci Rep
. 2020 Mar;
10(1):5097.
PMID: 32184438
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
4.
Bhudia N, Desai S, King N, Ancellin N, Grillot D, Barnes A, et al.
Sci Rep
. 2020 Jan;
10(1):1004.
PMID: 31969668
The experimental evidence that Adhesion G Protein-Coupled Receptors (aGPCRs) functionally couple to heterotrimeric G proteins has been emerging in incremental steps, but attributing biological significance to their G protein signalling...
5.
Foster J, Ueno S, Chen M, Harvey J, Dowell S, Irving A, et al.
Pharmacol Res Perspect
. 2019 Nov;
7(6):e00542.
PMID: 31768260
The G-protein-coupled receptor GPR132, also known as G2A, is activated by 9-hydroxyoctadecadienoic acid (9-HODE) and other oxidized fatty acids. Other suggested GPR132 agonists including lysophosphatidylcholine (LPC) have not been readily...
6.
Brown A, Castellano-Pellicena I, Haslam C, Nichols P, Dowell S
Pharmacology
. 2018 Oct;
102(5-6):324-331.
PMID: 30296786
Background/aims: CID16020046 blocks the effect of the lipid lysophosphatidylinositol (LPI) at its receptor, GPR55. CID16020046 and another antagonist, ML193, have been used to investigate GPR55-mediated effects of LPI on cells,...
7.
Weston C, Winfield I, Harris M, Hodgson R, Shah A, Dowell S, et al.
J Biol Chem
. 2016 Dec;
291(49):25763.
PMID: 27913664
No abstract available.
8.
Weston C, Winfield I, Harris M, Hodgson R, Shah A, Dowell S, et al.
J Biol Chem
. 2016 Aug;
291(42):21925-21944.
PMID: 27566546
The calcitonin gene-related peptide (CGRP) family of G protein-coupled receptors (GPCRs) is formed through the association of the calcitonin receptor-like receptor (CLR) and one of three receptor activity-modifying proteins (RAMPs)....
9.
Knight A, Hemmings J, Winfield I, Leuenberger M, Frattini E, Frenguelli B, et al.
J Med Chem
. 2016 Jan;
59(3):947-64.
PMID: 26756468
A series of N(6)-bicyclic and N(6)-(2-hydroxy)cyclopentyl derivatives of adenosine were synthesized as novel A1R agonists and their A1R/A2R selectivity assessed using a simple yeast screening platform. We observed that the...
10.
Demont E, Bailey J, Bit R, Brown J, Campbell C, Deeks N, et al.
J Med Chem
. 2016 Jan;
59(3):1003-20.
PMID: 26751273
FTY720 is the first oral small molecule approved for the treatment of people suffering from relapsing-remitting multiple sclerosis. It is a potent agonist of the S1P1 receptor, but its lack...