Simon I R Lane
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Explore the profile of Simon I R Lane including associated specialties, affiliations and a list of published articles.
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26
Citations
616
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Recent Articles
1.
Devitt G, Johnson P, Hanrahan N, Lane S, Vidale M, Sheth B, et al.
ACS Photonics
. 2024 Jan;
11(1):42-52.
PMID: 38249683
Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) has had a tremendous impact on humanity. Prevention of transmission by disinfection of surfaces and aerosols through a chemical-free method is highly desirable....
2.
Wu T, Lane S, Morgan S, Tang F, Jones K
J Cell Biol
. 2021 Aug;
220(10).
PMID: 34379093
The repetitive sequences of DNA centromeric regions form the structural basis for kinetochore assembly. Recently they were found to be transcriptionally active in mitosis, with their RNAs providing noncoding functions....
3.
Harrington J, Esteban L, Butement J, Vallejo A, Lane S, Sheth B, et al.
Lab Chip
. 2021 Jul;
21(17):3378-3386.
PMID: 34240097
The future of single cell diversity screens involves ever-larger sample sizes, dictating the need for higher throughput methods with low analytical noise to accurately describe the nature of the cellular...
4.
Jongen M, Holloway P, Lane S, Englyst N, McCarty O, West J
Cell Mol Bioeng
. 2021 Jun;
14(3):223-230.
PMID: 34109001
Introduction: Precision mapping of the functional structure of platelet populations holds great promise for the identification of hyper-reactive subtypes that are likely to be disease drivers, having value in prognostics...
5.
Lane S, Butement J, Harrington J, Underwood T, Shrimpton J, West J
Lab Chip
. 2019 Oct;
19(22):3771-3775.
PMID: 31608915
Particle sedimentation is deleterious to a tremendous variety of microfluidic applications. Using an open instrumentation approach we show that syringe rotation retains particles in a suspended state, providing a universal...
6.
Holloway P, Hallinan G, Hegde M, Lane S, Deinhardt K, West J
Lab Chip
. 2019 Mar;
19(8):1484-1489.
PMID: 30899932
Directional connectivity is required to develop accurate in vitro models of the nervous system. This research investigated the interaction of murine neuronal outgrowths with asymmetric microstructured geometries to provide insights...
7.
Manil-Segalen M, Luksza M, Kanaan J, Marthiens V, Lane S, Jones K, et al.
J Cell Biol
. 2018 Aug;
217(10):3416-3430.
PMID: 30082296
Mouse female meiotic spindles assemble from acentriolar microtubule-organizing centers (aMTOCs) that fragment into discrete foci. These are further sorted and clustered to form spindle poles, thus providing balanced forces for...
8.
Wu T, Lane S, Morgan S, Jones K
Nat Commun
. 2018 Jul;
9(1):2952.
PMID: 30054463
In the first meiotic division (MI) of oocytes, the cortically positioned spindle causes bivalent segregation in which only the centre-facing homologue pairs are retained. 'Selfish' chromosomes are known to exist,...
9.
Lane S, Jones K
J Cell Biol
. 2017 Oct;
216(12):3949-3957.
PMID: 28978643
The spindle assembly checkpoint (SAC) prevents chromosome missegregation by coupling anaphase onset with correct chromosome attachment and tension to microtubules. It does this by generating a diffusible signal from free...
10.
Lane S, Morgan S, Wu T, Collins J, Merriman J, Elinati E, et al.
Development
. 2017 Aug;
144(19):3475-3486.
PMID: 28851706
Mouse oocytes carrying DNA damage arrest in meiosis I, thereby preventing creation of embryos with deleterious mutations. The arrest is dependent on activation of the spindle assembly checkpoint, which results...