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Simon Hippenmeyer

Explore the profile of Simon Hippenmeyer including associated specialties, affiliations and a list of published articles. Areas
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Articles 64
Citations 2953
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Recent Articles
1.
Bose M, Talwar I, Suresh V, Mishra U, Biswas S, Yadav A, et al.
Elife . 2025 Mar; 13. PMID: 40085500
In the developing vertebrate central nervous system, neurons and glia typically arise sequentially from common progenitors. Here, we report that the transcription factor Forkhead Box G1 () regulates gliogenesis in...
2.
Cheung G, Pauler F, Hippenmeyer S
Methods Mol Biol . 2025 Jan; 2886:139-151. PMID: 39745639
Mosaic Analysis with Double Markers (MADM) represents a mouse genetic approach coupling differential fluorescent labeling to genetic manipulations in dividing cells and their lineages. MADM uniquely enables the generation and...
3.
Miranda O, Cheung G, Hippenmeyer S
Methods Mol Biol . 2024 Aug; 2831:283-299. PMID: 39134857
Mosaic Analysis with Double Markers (MADM) is a powerful genetic method typically used for lineage tracing and to disentangle cell autonomous and tissue-wide roles of candidate genes with single cell...
4.
Cheung G, Pauler F, Koppensteiner P, Hippenmeyer S
STAR Protoc . 2024 Jul; 5(3):103168. PMID: 38968076
The lineage relationship of clonally-related cells offers important insights into the ontogeny and cytoarchitecture of the brain in health and disease. Here, we provide a protocol to concurrently assess cell...
5.
Cheung G, Streicher C, Hippenmeyer S
STAR Protoc . 2024 Jun; 5(3):103157. PMID: 38935508
The generation of diverse cell types during development is fundamental to brain functions. We outline a protocol to quantitatively assess the clonal output of individual neural progenitors using mosaic analysis...
6.
Hansen A, Pauler F, Riedl M, Streicher C, Heger A, Laukoter S, et al.
Oxf Open Neurosci . 2024 Apr; 1:kvac009. PMID: 38596707
The mammalian neocortex is composed of diverse neuronal and glial cell classes that broadly arrange in six distinct laminae. Cortical layers emerge during development and defects in the developmental programs...
7.
Hansen A, Hippenmeyer S
STAR Protoc . 2024 Jan; 5(1):102795. PMID: 38165800
Mosaic analysis with double markers (MADM) technology enables the sparse labeling of genetically defined neurons. We present a protocol for time-lapse imaging of cortical projection neuron migration in mice using...
8.
Cheung G, Pauler F, Koppensteiner P, Krausgruber T, Streicher C, Schrammel M, et al.
Neuron . 2023 Dec; 112(2):230-246.e11. PMID: 38096816
The superior colliculus (SC) in the mammalian midbrain is essential for multisensory integration and is composed of a rich diversity of excitatory and inhibitory neurons and glia. However, the developmental...
9.
Amberg N, Cheung G, Hippenmeyer S
STAR Protoc . 2023 Dec; 5(1):102771. PMID: 38070137
Mosaic analysis with double markers (MADM) technology enables the generation of genetic mosaic tissue in mice and high-resolution phenotyping at the individual cell level. Here, we present a protocol for...
10.
Knaus L, Basilico B, Malzl D, Gerykova Bujalkova M, Smogavec M, Schwarz L, et al.
Cell . 2023 Mar; 186(9):1950-1967.e25. PMID: 36996814
Little is known about the critical metabolic changes that neural cells have to undergo during development and how temporary shifts in this program can influence brain circuitries and behavior. Inspired...