Simon Dohrmann
Overview
Explore the profile of Simon Dohrmann including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
367
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0
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Recent Articles
1.
Stream A, Corriden R, Dohrmann S, Gallo R, Nizet V, Anderson E
Infect Microbes Dis
. 2024 Jul;
6(2):65-73.
PMID: 38952747
Vitamin A and its biologically active derivative, retinoic acid (RA), are important for many immune processes. RA, in particular, is essential for the development of immune cells, including neutrophils, which...
2.
Denholtz M, Zhu Y, He Z, Lu H, Isoda T, Dohrmann S, et al.
Genes Dev
. 2020 Jan;
34(3-4):149-165.
PMID: 31919189
Differentiating neutrophils undergo large-scale changes in nuclear morphology. How such alterations in structure are established and modulated upon exposure to microbial agents is largely unknown. Here, we found that prior...
3.
Lizcano A, Secundino I, Dohrmann S, Corriden R, Rohena C, Diaz S, et al.
Blood
. 2017 Apr;
129(23):3100-3110.
PMID: 28416510
Healthy blood neutrophils are functionally quiescent in the bloodstream, have a short lifespan, and exit the circulation to carry out innate immune functions, or undergo rapid apoptosis and macrophage-mediated clearance...
4.
Dohrmann S, LaRock C, Anderson E, Cole J, Ryali B, Stewart C, et al.
Sci Rep
. 2017 Feb;
7:43039.
PMID: 28220899
Histones are essential elements of chromatin structure and gene regulation in eukaryotes. An unexpected attribute of these nuclear proteins is their antimicrobial activity. A framework for histone release and function...
5.
van Wijk X, Dohrmann S, Hallstrom B, Li S, Voldborg B, Meng B, et al.
mBio
. 2017 Jan;
8(1).
PMID: 28074024
Importance: Pathogenic bacteria penetrate host cellular barriers by attachment to extracellular matrix molecules, such as proteoglycans, laminins, and collagens, leading to invasion of epithelial and endothelial cells. Here, we show...
6.
Flores R, Dohrmann S, Schaal C, Hakkim A, Nizet V, Corriden R
Front Immunol
. 2016 Dec;
7:566.
PMID: 28003814
Raloxifene is a selective estrogen receptor modulator typically prescribed for the prevention/treatment of osteoporosis in postmenopausal women. Although raloxifene is known to have anti-inflammatory properties, its effects on human neutrophils,...
7.
Dohrmann S, Cole J, Nizet V
PLoS Pathog
. 2016 Jul;
12(7):e1005682.
PMID: 27467389
No abstract available.
8.
Kumaraswamy M, Lin L, Olson J, Sun C, Nonejuie P, Corriden R, et al.
J Antimicrob Chemother
. 2016 Feb;
71(5):1264-9.
PMID: 26832758
Objectives: The Gram-negative bacillus Stenotrophomonas maltophilia (SM) is an emerging MDR opportunistic pathogen. Recent studies identify a potentially relevant activity of azithromycin against Gram-negative bacteria overlooked in standard bacteriological testing....
9.
Uchiyama S, Dohrmann S, Timmer A, Dixit N, Ghochani M, Bhandari T, et al.
Front Immunol
. 2015 Dec;
6:581.
PMID: 26635795
Group A Streptococcus (GAS) causes a wide range of human infections, ranging from simple pharyngitis to life-threatening necrotizing fasciitis and toxic shock syndrome. A globally disseminated clone of M1T1 GAS...
10.
LaRock C, Dohrmann S, Todd J, Corriden R, Olson J, Johannssen T, et al.
Cell Host Microbe
. 2015 Oct;
18(4):471-7.
PMID: 26468750
The antimicrobial peptide LL-37 is generated upon proteolytic cleavage of cathelicidin and limits invading pathogens by directly targeting microbial membranes as well as stimulating innate immune cell function. However, some...