Simon de Givry
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Explore the profile of Simon de Givry including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
273
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Recent Articles
1.
Pomies L, Brouard C, Durufle H, Maigne E, Carre C, Gody L, et al.
Bioinformatics
. 2022 Jul;
38(17):4127-4134.
PMID: 35792837
Motivation: Inferring gene regulatory networks in non-independent genetically related panels is a methodological challenge. This hampers evolutionary and biological studies using heterozygote individuals such as in wild sunflower populations or...
2.
Beuvin F, de Givry S, Schiex T, Verel S, Simoncini D
Proteins
. 2021 Jul;
89(11):1522-1529.
PMID: 34228826
Structure-based computational protein design (CPD) refers to the problem of finding a sequence of amino acids which folds into a specific desired protein structure, and possibly fulfills some targeted biochemical...
3.
Viricel C, de Givry S, Schiex T, Barbe S
Bioinformatics
. 2018 Feb;
34(15):2581-2589.
PMID: 29474517
Motivation: Accurate and economic methods to predict change in protein binding free energy upon mutation are imperative to accelerate the design of proteins for a wide range of applications. Free...
4.
Simoncini D, Allouche D, de Givry S, Delmas C, Barbe S, Schiex T
J Chem Theory Comput
. 2015 Nov;
11(12):5980-9.
PMID: 26610100
In Computational Protein Design (CPD), assuming a rigid backbone and amino-acid rotamer library, the problem of finding a sequence with an optimal conformation is NP-hard. In this paper, using Dunbrack's...
5.
Traore S, Allouche D, Andre I, de Givry S, Katsirelos G, Schiex T, et al.
Bioinformatics
. 2013 Jul;
29(17):2129-36.
PMID: 23842814
Motivation: The main challenge for structure-based computational protein design (CPD) remains the combinatorial nature of the search space. Even in its simplest fixed-backbone formulation, CPD encompasses a computationally difficult NP-hard...
6.
Vignes M, Vandel J, Allouche D, Ramadan-Alban N, Cierco-Ayrolles C, Schiex T, et al.
PLoS One
. 2012 Jan;
6(12):e29165.
PMID: 22216195
Modern technologies and especially next generation sequencing facilities are giving a cheaper access to genotype and genomic data measured on the same sample at once. This creates an ideal situation...
7.
Servin B, de Givry S, Faraut T
Bioinformatics
. 2010 Nov;
26(24):3035-42.
PMID: 21076149
Motivation: Genome maps are imperative to address the genetic basis of the biology of an organism. While a growing number of genomes are being sequenced providing the ultimate genome maps-this...
8.
Marques E, de Givry S, Stothard P, Murdoch B, Wang Z, Womack J, et al.
BMC Genomics
. 2007 Jul;
8:254.
PMID: 17655763
Background: Radiation hybrid (RH) maps are considered to be a tool of choice for fine mapping closely linked loci, considering that the resolution of linkage maps is determined by the...
9.
de Givry S, Bouchez M, Chabrier P, Milan D, Schiex T
Bioinformatics
. 2004 Dec;
21(8):1703-4.
PMID: 15598829
Unlabelled: CAR(H)(T)A GENE: is an integrated genetic and radiation hybrid (RH) mapping tool which can deal with multiple populations, including mixtures of genetic and RH data. CAR(H)(T)A GENE: performs multipoint...