Sophie Barbe
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Explore the profile of Sophie Barbe including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
405
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Recent Articles
1.
Bouchiba Y, Esque J, Cottret L, Marechaux M, Gaston M, Gasciolli V, et al.
Protein Sci
. 2022 May;
31(6):e4327.
PMID: 35634776
N-acetylglucosamine containing compounds acting as pathogenic or symbiotic signals are perceived by plant-specific Lysin Motif Receptor-Like Kinases (LysM-RLKs). The molecular mechanisms of this perception are not fully understood, notably those...
2.
Bouchiba Y, Ruffini M, Schiex T, Barbe S
Methods Mol Biol
. 2022 Mar;
2405:361-382.
PMID: 35298822
Miniprotein binders hold a great interest as a class of drugs that bridges the gap between monoclonal antibodies and small molecule drugs. Like monoclonal antibodies, they can be designed to...
3.
Cox N, Charlier C, Vijayaraj R, De La Mare M, Barbe S, Andre I, et al.
Biochem Biophys Res Commun
. 2021 Dec;
589:223-228.
PMID: 34929445
Covalent protein complexes have been used to assemble enzymes in large scaffolds for biotechnology purposes. Although the catalytic mechanism of the covalent linking of such proteins is well known, the...
4.
Defresne M, Barbe S, Schiex T
Int J Mol Sci
. 2021 Nov;
22(21).
PMID: 34769173
Computational Protein Design (CPD) has produced impressive results for engineering new proteins, resulting in a wide variety of applications. In the past few years, various efforts have aimed at replacing...
5.
Pelus A, Bordes G, Barbe S, Bouchiba Y, Burnard C, Cortes J, et al.
Biomater Sci
. 2021 Oct;
9(22):7444-7455.
PMID: 34647546
The development of protein and microorganism engineering have led to rising expectations of biotechnology in the design of emerging biomaterials, putatively of high interest to reduce our dependence on fossil...
6.
Benkoulouche M, Ben Imeddourene A, Barel L, Lefebvre D, Fanuel M, Rogniaux H, et al.
Sci Rep
. 2021 Oct;
11(1):20294.
PMID: 34645865
Enzyme engineering approaches have allowed to extend the collection of enzymatic tools available for synthetic purposes. However, controlling the regioselectivity of the reaction remains challenging, in particular when dealing with...
7.
Boudsocq F, Salhi M, Barbe S, Bouet J
Genes (Basel)
. 2021 Sep;
12(9).
PMID: 34573327
Accurate DNA segregation is essential for faithful inheritance of genetic material. In bacteria, this process is mainly ensured by partition systems composed of two proteins, ParA and ParB, and a...
8.
Yagi S, Padhi A, Vucinic J, Barbe S, Schiex T, Nakagawa R, et al.
J Am Chem Soc
. 2021 Sep;
143(39):15998-16006.
PMID: 34559526
The extant complex proteins must have evolved from ancient short and simple ancestors. The double-ψ β-barrel (DPBB) is one of the oldest protein folds and conserved in various fundamental enzymes,...
9.
Vucinic J, Novikov G, Montanier C, Dumon C, Schiex T, Barbe S
Int J Mol Sci
. 2021 Jun;
22(11).
PMID: 34073139
With the growing need for renewable sources of energy, the interest for enzymes capable of biomass degradation has been increasing. In this paper, we consider two different xylanases from the...
10.
Bouchiba Y, Cortes J, Schiex T, Barbe S
Protein Eng Des Sel
. 2021 May;
34.
PMID: 33959778
Computational protein design (CPD) is a powerful technique for engineering new proteins, with both great fundamental implications and diverse practical interests. However, the approximations usually made for computational efficiency, using...