Simon A McG Thom
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Explore the profile of Simon A McG Thom including associated specialties, affiliations and a list of published articles.
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Citations
785
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Recent Articles
1.
Martinez-Perez M, Hughes A, Thom S, Parker K, Witt N
R Soc Open Sci
. 2023 Jun;
10(6):230065.
PMID: 37351500
This study investigated the possibility of using low-cost, handheld, retinal imaging devices for the automatic extraction of quantifiable measures of retinal blood vessels. Initially, the available handheld devices were compared...
2.
Gu B, Huang Y, Manchester E, Hughes A, Thom S, Chen R, et al.
Pharm Res
. 2022 Jan;
39(1):41-56.
PMID: 35044591
Purpose: This study establishes a multiphysics simulation platform for both conventional and targeted thrombolysis using tissue plasminogen activator (tPA). Based on our computational results, the effects of therapeutic parameters on...
3.
Sluyter J, Hughes A, Camargo Jr C, Thom S, Parker K, Hametner B, et al.
Hypertension
. 2019 Aug;
74(4):921-928.
PMID: 31446803
Clustering of arterial blood pressure (BP) waveform parameters could summarize complex information into distinct elements, which could be used to investigate cumulative (nonredundant) associations. We investigated this hypothesis in a...
4.
Jackson M, Wood N, Zhao S, Augst A, Wolfe J, Gedroyc W, et al.
Artery Res
. 2019 Mar;
3(1):32-38.
PMID: 30881518
Background: Venous grafts commonly develop myointimal hyperplasia, which can lead to stenoses and, ultimately, with expression of adhesion molecules, lumenal occlusion. The aim of the present study was to investigate...
5.
Sluyter J, Camargo Jr C, Stewart A, Waayer D, Lawes C, Toop L, et al.
J Am Heart Assoc
. 2017 Oct;
6(10).
PMID: 29066444
Background: The effects of monthly, high-dose, long-term (≥1-year) vitamin D supplementation on central blood pressure (BP) parameters are unknown. Methods And Results: A total of 517 adults (58% male, aged...
6.
Hughes A, Falaschetti E, Witt N, Wijetunge S, Thom S, Tillin T, et al.
Stroke
. 2016 Oct;
47(11):2862-2864.
PMID: 27729577
Background And Purpose: Abnormalities of the retinal circulation may be associated with cerebrovascular disease. We investigated associations between retinal microvascular abnormalities and (1) strokes and subclinical cerebral infarcts and (2)...
7.
Hussain S, Kahonen M, Raitakari O, Skilton M, Witt N, Chaturvedi N, et al.
Microcirculation
. 2015 Mar;
22(4):285-93.
PMID: 25731939
Objective: We hypothesized that preterm birth and being born SGA would be associated with changes in retinal microvascular architecture and that these changes would be more marked among those born...
8.
Tapp R, Hussain S, Battista J, Hutri-Kahonen N, Lehtimaki T, Hughes A, et al.
Microcirculation
. 2015 Jan;
22(2):146-55.
PMID: 25559612
Objective: The present study examined the impact of BP from childhood to mid-adulthood on retinal microvascular architecture. Methods: The Cardiovascular Risk in Young Finns Study included children aged 3-18 years,...
9.
Davies J, Lacy P, Tillin T, Collier D, Cruickshank J, Francis D, et al.
Hypertension
. 2014 May;
64(1):60-8.
PMID: 24821941
Excess pressure integral (XSPI), a new index of surplus work performed by the left ventricle, can be calculated from blood pressure waveforms and may indicate circulatory dysfunction. We investigated whether...
10.
Hughes A, Park C, Davies J, Francis D, Thom S, Mayet J, et al.
PLoS One
. 2013 Apr;
8(3):e59371.
PMID: 23544061
Objectives: Augmentation index (AIx) is widely used as a measure of wave reflection. We compared the relationship between AIx and age, height and sex with 'gold standard' measures of wave...