Simon A McG Thom
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Explore the profile of Simon A McG Thom including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Tapp R, Ness A, Williams C, Howe L, Tilling K, Witt N, et al.
Microcirculation
. 2013 Mar;
20(7):609-16.
PMID: 23517335
Objectives: We hypothesized that trajectories of adiposity across childhood would be associated with retinal microcirculatory diameters at age 12 years, independent of BP. Methods: The ALSPAC followed a cohort of...
12.
Bathula R, Hughes A, Panerai R, Potter J, Thom S, Tillin T, et al.
Int J Epidemiol
. 2011 Jul;
40(6):1490-8.
PMID: 21724578
Background: South Asians have a 1.5-fold increased stroke mortality compared with Europeans, despite similar blood pressures (BP). We hypothesized that it is the greater hyperglycaemia in South Asians that increases...
13.
Starmans-Kool M, Stanton A, Xu Y, Thom S, Parker K, Hughes A
J Appl Physiol (1985)
. 2010 Nov;
110(2):468-71.
PMID: 21088211
Dietary salt intake is associated with high brachial blood pressure (BP) and increased risk of cardiovascular disease. We investigated whether changes in dietary salt intake are associated with changes in...
14.
Witt N, Chapman N, Thom S, Stanton A, Parker K, Hughes A
Artery Res
. 2010 Nov;
4(3):75-80.
PMID: 21072124
Conventionally, the relationship between parent and daughter vessels at vascular bifurcations has been expressed by the junction exponent (x), and deviations of this parameter from the optimal conditions predicted by...
15.
Manisty C, Mayet J, Tapp R, Parker K, Sever P, Poulter N, et al.
J Am Coll Cardiol
. 2010 Jul;
56(1):24-30.
PMID: 20620713
Objectives: This study investigated whether wave reflection measured by wave intensity analysis predicts future cardiovascular events in individuals with hypertension and sought to establish whether this relationship is independent of...
16.
Tapp R, Sharp A, Stanton A, OBrien E, Chaturvedi N, Poulter N, et al.
J Am Coll Cardiol
. 2010 Apr;
55(17):1875-81.
PMID: 20413040
Objectives: We hypothesized that an amlodipine-based regimen would have more favorable effects on left ventricular (LV) diastolic function. Background: Different antihypertensive therapies may vary in their effect on LV diastolic...
17.
Torii R, Keegan J, Wood N, Dowsey A, Hughes A, Yang G, et al.
Ann Biomed Eng
. 2010 Apr;
38(8):2606-20.
PMID: 20364324
The aim of this study was to develop a fully subject-specific model of the right coronary artery (RCA), including dynamic vessel motion, for computational analysis to assess the effects of...
18.
Sharp A, Tapp R, Thom S, Francis D, Hughes A, Stanton A, et al.
Eur Heart J
. 2009 Nov;
31(6):747-52.
PMID: 19942604
Aims: Patients with controlled hypertension are at risk of future cardiac events, but predicting first events remains difficult. We hypothesized that modern echocardiographic measures of left ventricular diastolic function may...
19.
Manisty C, Mayet J, Tapp R, Sever P, Poulter N, Thom S, et al.
Hypertension
. 2009 Sep;
54(5):1009-13.
PMID: 19720956
Hydroxymethylglutaryl-CoA reductase inhibitors (statins) reduce cardiovascular events in hypertensive subjects, but their effect on carotid BP, pressure augmentation, and wave reflection is unknown. We compared the effect of atorvastatin with...
20.
Manisty C, Zambanini A, Parker K, Davies J, Francis D, Mayet J, et al.
Hypertension
. 2009 Aug;
54(4):724-30.
PMID: 19704107
Antihypertensive agents may differ in their effects on central systolic blood pressure, and this may contribute to treatment-related differences in cardiovascular outcomes. In a substudy of the Anglo-Scandinavian Cardiac Outcome...