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Silviu A Bacanu

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Articles 9
Citations 1397
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Recent Articles
1.
Zaur A, Bacanu S, Amstadter A, Sheerin C
Mil Psychol . 2024 Aug; :1-11. PMID: 39208338
PTSD and AUD are frequently comorbid post-trauma outcomes. Much remains unknown about shared risk factors as PTSD and AUD work tends to be conducted in isolation. We examined how self-report...
2.
Gentry A, Alexander J, Ahangari M, Peterson R, Miles M, Bettinger J, et al.
PLoS One . 2023 Apr; 18(4):e0283985. PMID: 37098020
Background: Variation in genes involved in ethanol metabolism has been shown to influence risk for alcohol dependence (AD) including protective loss of function alleles in ethanol metabolizing genes. We therefore...
3.
Trubetskoy V, Pardinas A, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli T, et al.
Nature . 2022 Apr; 604(7906):502-508. PMID: 35396580
Schizophrenia has a heritability of 60-80%, much of which is attributable to common risk alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and...
4.
Mignogna K, Bacanu S, Riley B, Wolen A, Miles M
PLoS One . 2019 Apr; 14(4):e0202063. PMID: 31017905
Genome-wide association studies on alcohol dependence, by themselves, have yet to account for the estimated heritability of the disorder and provide incomplete mechanistic understanding of this complex trait. Integrating brain...
5.
Docherty A, Fonseca-Pedrero E, Debbane M, Chan R, Linscott R, Jonas K, et al.
Schizophr Bull . 2018 May; 44(suppl_2):S460-S467. PMID: 29788473
The latent structure of schizotypy and psychosis-spectrum symptoms remains poorly understood. Furthermore, molecular genetic substrates are poorly defined, largely due to the substantial resources required to collect rich phenotypic data...
6.
Docherty A, Moscati A, Dick D, Savage J, Salvatore J, Cooke M, et al.
Psychol Med . 2017 Nov; 48(11):1814-1823. PMID: 29173193
Background: Identifying genetic relationships between complex traits in emerging adulthood can provide useful etiological insights into risk for psychopathology. College-age individuals are under-represented in genomic analyses thus far, and the...
7.
Adkins A, Hack L, Bigdeli T, Williamson V, McMichael G, Mamdani M, et al.
Alcohol Clin Exp Res . 2017 Feb; 41(5):911-928. PMID: 28226201
Background: Alcohol dependence (AD) shows evidence for genetic liability, but genes influencing risk remain largely unidentified. Methods: We conducted a genomewide association study in 706 related AD cases and 1,748...
8.
Docherty A, Edwards A, Yang F, Peterson R, Sawyers C, Adkins D, et al.
Depress Anxiety . 2017 Feb; 34(5):446-452. PMID: 28152564
Background: The extent to which earlier age of onset (AO) is a reflection of increased genetic risk for major depression (MD) is still unknown. Previous biometrical research has provided mixed...
9.
Marshall C, Howrigan D, Merico D, Thiruvahindrapuram B, Wu W, Greer D, et al.
Nat Genet . 2016 Nov; 49(1):27-35. PMID: 27869829
Copy number variants (CNVs) have been strongly implicated in the genetic etiology of schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk has been hampered by limited...