Silvio Parodi
Overview
Explore the profile of Silvio Parodi including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
21
Citations
193
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Sommariva S, Caviglia G, Ravera S, Frassoni F, Benvenuto F, Tortolina L, et al.
Sci Rep
. 2021 Oct;
11(1):19602.
PMID: 34599254
Colorectal cancer (CRC) is one of the most deadly and commonly diagnosed tumors worldwide. Several genes are involved in its development and progression. The most frequent mutations concern APC, KRAS,...
2.
Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial
Castagnino N, Maffei M, Tortolina L, Zoppoli G, Piras D, Nencioni A, et al.
Wiley Interdiscip Rev Syst Biol Med
. 2016 May;
8(4):314-36.
PMID: 27240214
Current colorectal cancer (CRC) treatment guidelines are primarily based on clinical features, such as cancer stage and grade. However, outcomes may be improved using molecular treatment guidelines. Potentially useful biomarkers...
3.
Systems Medicine in Oncology: Signaling Network Modeling and New-Generation Decision-Support Systems
Parodi S, Riccardi G, Castagnino N, Tortolina L, Maffei M, Zoppoli G, et al.
Methods Mol Biol
. 2015 Dec;
1386:181-219.
PMID: 26677185
Two different perspectives are the main focus of this book chapter: (1) A perspective that looks to the future, with the goal of devising rational associations of targeted inhibitors against...
4.
Tortolina L, Duffy D, Maffei M, Castagnino N, Carmody A, Kolch W, et al.
Oncotarget
. 2015 Feb;
6(7):5041-58.
PMID: 25671297
The interconnected network of pathways downstream of the TGFβ, WNT and EGF-families of receptor ligands play an important role in colorectal cancer pathogenesis.We studied and implemented dynamic simulations of multiple...
5.
De Ambrosi C, Barla A, Tortolina L, Castagnino N, Pesenti R, Verri A, et al.
Math Biosci Eng
. 2013 Jan;
10(1):103-20.
PMID: 23311364
We started offering an introduction to very basic aspects of molecular biology, for the reader coming from computer sciences, information technology, mathematics. Similarly we offered a minimum of information about...
6.
7.
Zoppoli G, Cea M, Soncini D, Fruscione F, Rudner J, Moran E, et al.
Exp Hematol
. 2010 Aug;
38(11):979-88.
PMID: 20696207
Objective: The nicotinamide phosphoribosyltransferase (Nampt) inhibitor APO866 depletes intracellular nicotinamide adenine dinucleotide (NAD(+)) and shows promising anticancer activity in preclinical studies. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) binds to plasma...
8.
Zoppoli G, Moran E, Soncini D, Cea M, Garuti A, Rocco I, et al.
Curr Cancer Drug Targets
. 2010 Jan;
10(2):168-75.
PMID: 20088787
Lapatinib, a dual HER2 and EGFR tyrosine kinase inhibitor is highly active in HER2+ breast cancer. However, its efficacy is limited by either primary or acquired resistance. Although mutations in...
9.
Ghiotto F, Fais F, Tenca C, Tomati V, Morabito F, Casciaro S, et al.
Cancer Biol Ther
. 2009 Jan;
8(3):263-71.
PMID: 19164937
B-cell chronic lymphocytic leukemia (B-CLL) is the most common leukemia in human adults of the Western world and no definitive cure is yet available. The disease is characterized by accumulation...
10.
Ponassi R, Biasotti B, Tomati V, Bruno S, Poggi A, Malacarne D, et al.
Cell Cycle
. 2008 Oct;
7(20):3211-24.
PMID: 18843207
BH3-only members of the Bcl-2 family exert a fundamental role in apoptosis induction. This work focuses on the development of a novel peptidic molecule based on the BH3 domain of...