Silvia Thoene
Overview
Explore the profile of Silvia Thoene including associated specialties, affiliations and a list of published articles.
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10
Citations
192
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Recent Articles
1.
Haebe S, Keay W, Alig S, Mohr A, Martin L, Heide M, et al.
Br J Haematol
. 2021 Dec;
196(6):1381-1387.
PMID: 34967008
Relapsed follicular lymphoma (FL) can arise from common progenitor cells (CPCs). Conceptually, CPC-defining mutations are somatic alterations shared by the initial and relapsed tumours, mostly B-cell leukaemia/lymphoma 2 (BCL2)/immunoglobulin heavy...
2.
Thoene S, Mandal T, Vegi N, Quintanilla-Martinez L, Rosler R, Wiese S, et al.
Blood Adv
. 2019 Nov;
3(22):3729-3739.
PMID: 31770439
Acute erythroid leukemia (AEL) is a rare and aggressive form of acute leukemia, the biology of which remains poorly understood. Here we demonstrate that the ParaHox gene CDX4 is expressed...
3.
Rawat V, Gotze M, Rasalkar A, Vegi N, Ihme S, Thoene S, et al.
Haematologica
. 2019 Sep;
105(6):e285-e289.
PMID: 31558674
No abstract available.
4.
Albers J, Ammon T, Gosmann D, Audehm S, Thoene S, Winter C, et al.
Life Sci Alliance
. 2019 Mar;
2(2).
PMID: 30877233
Adoptive transfer of TCR transgenic T cells holds great promise for treating various cancers. So far, mainly semi-randomly integrating vectors have been used to genetically modify T cells. These carry...
5.
Hagl B, Spielberger B, Thoene S, Bonnal S, Mertes C, Winter C, et al.
Sci Rep
. 2018 Nov;
8(1):16719.
PMID: 30425284
In hyper-IgE syndromes (HIES), a group of primary immunodeficiencies clinically overlapping with atopic dermatitis, early diagnosis is crucial to initiate appropriate therapy and prevent irreversible complications. Identification of underlying gene...
6.
Patzelt T, Keppler S, Gorka O, Thoene S, Wartewig T, Reth M, et al.
Proc Natl Acad Sci U S A
. 2018 Mar;
115(12):3120-3125.
PMID: 29507226
The transcription factor Foxp1 is critical for early B cell development. Despite frequent deregulation of Foxp1 in B cell lymphoma, the physiological functions of Foxp1 in mature B cells remain...
7.
Seitz A, Thoene S, Bietenbeck A, Nawroth R, Tauber R, Thalgott M, et al.
Eur Urol
. 2017 Aug;
72(5):828-834.
PMID: 28818355
Background: It has been demonstrated that androgen receptor splice variant 7 (AR-V7) expression in circulating tumor cells (CTCs) predicts poor treatment response in metastatic castration-resistant prostate cancer (mCRPC) patients treated...
8.
Berg T, Thoene S, Yap D, Wee T, Schoeler N, Rosten P, et al.
Blood
. 2014 May;
123(25):3914-24.
PMID: 24802772
The histone methyltransferase EZH2 is frequently mutated in germinal center-derived diffuse large B-cell lymphoma and follicular lymphoma. To further characterize these EZH2 mutations in lymphomagenesis, we generated a mouse line...
9.
Rawat V, Arseni N, Ahmed F, Mulaw M, Thoene S, Heilmeier B, et al.
Proc Natl Acad Sci U S A
. 2010 Sep;
107(39):16946-51.
PMID: 20833819
Recent data indicate that a variety of regulatory molecules active in embryonic development may also play a role in the regulation of early hematopoiesis. Here we report that the human...
10.
Rawat V, Thoene S, Naidu V, Arseni N, Heilmeier B, Metzeler K, et al.
Blood
. 2007 Sep;
111(1):309-19.
PMID: 17855634
The mechanisms underlying deregulation of HOX gene expression in AML are poorly understood. The ParaHox gene CDX2 was shown to act as positive upstream regulator of several HOX genes. In...