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Silvia Scolari

Explore the profile of Silvia Scolari including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 224
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Recent Articles
1.
Khmelinskaia A, Marques J, Bastos A, Antunes C, Bento-Oliveira A, Scolari S, et al.
Front Cell Dev Biol . 2020 Jun; 8:337. PMID: 32596234
Here, biophysical properties of membranes enriched in three metabolically related sterols are analyzed both and . Unlike cholesterol and ergosterol, the common metabolic precursor zymosterol is unable to induce the...
2.
Liebsch F, Aurousseau M, Bethge T, McGuire H, Scolari S, Herrmann A, et al.
J Biol Chem . 2017 Jun; 292(32):13258-13270. PMID: 28637867
The β-secretase (BACE1) initiates processing of the amyloid precursor protein (APP) into Aβ peptides, which have been implicated as central players in the pathology of Alzheimer disease. BACE1 has been...
3.
Scolari S, Imkeller K, Jolmes F, Veit M, Herrmann A, Schwarzer R
Cell Microbiol . 2015 Aug; 18(1):125-36. PMID: 26243691
Viral glycoproteins are highly variable in their primary structure, but on the other hand feature a high functional conservation to fulfil their versatile tasks during the pathogenic life cycle. Typically,...
4.
Schwarzer R, Levental I, Gramatica A, Scolari S, Buschmann V, Veit M, et al.
Cell Microbiol . 2014 May; 16(10):1565-81. PMID: 24844300
Enveloped viruses often use membrane lipid rafts to assemble and bud, augment infection and spread efficiently. However, the molecular bases and functional consequences of the partitioning of viral glycoproteins into...
5.
Veit M, Engel S, Thaa B, Scolari S, Herrmann A
Cell Microbiol . 2012 Oct; 15(2):179-89. PMID: 23057766
Influenza virus is thought to assemble in raft domains of the plasma membrane, but many of the conclusions were based on (controversial) Triton extraction experiments. Here we review how sophisticated...
6.
Gutschow M, Schlenk M, Gab J, Paskaleva M, Alnouri M, Scolari S, et al.
J Med Chem . 2012 Mar; 55(7):3331-41. PMID: 22409573
2-(Acyl)amino-4H-3,1-benzothiazin-4-ones and related thienothiazinones were identified as structurally novel antagonists at adenosine receptors (ARs). 6-Methyl-2-benzoylamino-4H-3,1-benzothiazin-4-one (10d) was found to be a balanced AR antagonist with affinity for all human (h)...
7.
Bastos A, Scolari S, Stockl M, de Almeida R
Methods Enzymol . 2012 Jan; 504:57-81. PMID: 22264529
Lipid domains are part of the current description of cell membranes and their involvement in many fundamental cellular processes is currently acknowledged. However, their study in living cells is still...
8.
Schreiber G, Barberis M, Scolari S, Klaus C, Herrmann A, Klipp E
FASEB J . 2011 Oct; 26(2):546-54. PMID: 22002907
Sic1, cyclin-dependent kinase inhibitor of budding yeast, is synthesized in anaphase and largely degraded at the S-phase onset to regulate timing of DNA synthesis. Sic1 interacts with phase-specific B-type cyclin...
9.
Loew M, Springer R, Scolari S, Altenbrunn F, Seitz O, Liebscher J, et al.
J Am Chem Soc . 2010 Oct; 132(45):16066-72. PMID: 20964327
Lipid domains in mammalian plasma membranes serve as platforms for specific recruitment or separation of proteins involved in various functions. Here, we have applied this natural strategy of lateral separation...
10.
Scolari S, Muller K, Bittman R, Herrmann A, Muller P
Biochemistry . 2010 Sep; 49(42):9027-31. PMID: 20863067
Seminal plasma proteins of the fibronectin type II (Fn2) family modulate mammalian spermatogenesis by triggering the release of the lipids phosphatidylcholine and cholesterol from sperm cells. Whereas the specific interaction...