Silvia Del Guerra
Overview
Explore the profile of Silvia Del Guerra including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
33
Citations
1708
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0
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Recent Articles
1.
Bosi E, Marselli L, Suleiman M, Tesi M, De Luca C, Del Guerra S, et al.
NAR Genom Bioinform
. 2022 Nov;
4(4):lqac084.
PMID: 36415826
A sensible control of hormone secretion from pancreatic islets requires concerted inter-cellular communications, but a comprehensive picture of the whole islet interactome is presently missing. Single-cell transcriptomics allows to overcome...
2.
Azzarello F, Pesce L, De Lorenzi V, Ferri G, Tesi M, Del Guerra S, et al.
Commun Biol
. 2022 Nov;
5(1):1232.
PMID: 36371562
Here we use a combination of two-photon Fluorescence Lifetime Imaging Microscopy (FLIM) of NAD(P)H free/bound ratio in living HIs with post-fixation, immunofluorescence-based, cell-type identification. FLIM allowed to measure variations in...
3.
Giusti L, Tesi M, Ciregia F, Marselli L, Zallocco L, Suleiman M, et al.
Cells
. 2022 Aug;
11(15).
PMID: 35954309
Metformin, a drug widely used in type 2 diabetes (T2D), has been shown to protect human β-cells exposed to gluco- and/or lipotoxic conditions and those in islets from T2D donors....
4.
Suleiman M, Marselli L, Cnop M, Eizirik D, De Luca C, Femia F, et al.
Int J Mol Sci
. 2022 Jul;
23(13).
PMID: 35806437
Type 2 diabetes (T2D) has been considered a relentlessly worsening disease, due to the progressive deterioration of the pancreatic beta cell functional mass. Recent evidence indicates, however, that remission of...
5.
Marselli L, Bosi E, De Luca C, Del Guerra S, Tesi M, Suleiman M, et al.
Int J Mol Sci
. 2021 Nov;
22(22).
PMID: 34829980
Arginase 2 (ARG2) is a manganese metalloenzyme involved in several tissue specific processes, from physiology to pathophysiology. It is variably expressed in extra-hepatic tissues and is located in the mitochondria....
6.
Volkmar M, Dedeurwaerder S, Cunha D, Ndlovu M, Defrance M, Deplus R, et al.
EMBO J
. 2012 Feb;
31(6):1405-26.
PMID: 22293752
In addition to genetic predisposition, environmental and lifestyle factors contribute to the pathogenesis of type 2 diabetes (T2D). Epigenetic changes may provide the link for translating environmental exposures into pathological...
7.
Paola R, Caporarello N, Marucci A, Dimatteo C, Iadicicco C, Del Guerra S, et al.
PLoS One
. 2011 May;
6(5):e19462.
PMID: 21573217
The aim of this study was to deeper investigate the mechanisms through which ENPP1, a negative modulator of insulin receptor (IR) activation, plays a role on insulin signaling, insulin secretion...
8.
Marchetti P, Lupi R, Del Guerra S, Bugliani M, Marselli L, Boggi U
Adv Exp Med Biol
. 2010 Mar;
654:501-14.
PMID: 20217512
beta-cell dysfunction is central to the onset and progression of type 2 diabetes. Reduced islet number and/or diminished beta-cell mass/volume in the pancreas of type 2 diabetic subjects have been...
9.
Cauchi S, Del Guerra S, Choquet H, DAleo V, Groves C, Lupi R, et al.
Mol Genet Metab
. 2010 Feb;
100(1):77-82.
PMID: 20138556
Background: The C-allele of rs13266634 located in SLC30A8 (ZNT8) has been strongly associated with decreased insulin release and with type 2 diabetes (T2D) susceptibility in some but not all studies....
10.
Marchetti P, Lupi R, Del Guerra S, Bugliani M, DAleo V, Occhipinti M, et al.
Diabetes Care
. 2009 Oct;
32 Suppl 2:S178-83.
PMID: 19875548
No abstract available.