Silvia D M Santos
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Explore the profile of Silvia D M Santos including associated specialties, affiliations and a list of published articles.
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10
Citations
548
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Recent Articles
1.
Pal D, Patel M, Boulet F, Sundarraj J, Grant O, Branco M, et al.
Nat Struct Mol Biol
. 2023 Jun;
30(7):935-947.
PMID: 37308596
Mammalian genomes harbor abundant transposable elements (TEs) and their remnants, with numerous epigenetic repression mechanisms enacted to silence TE transcription. However, TEs are upregulated during early development, neuronal lineage, and...
2.
Cable J, Elowitz M, Domingos A, Habib N, Itzkovitz S, Hamidzada H, et al.
Ann N Y Acad Sci
. 2021 Oct;
1506(1):74-97.
PMID: 34605044
Single cell biology has the potential to elucidate many critical biological processes and diseases, from development and regeneration to cancer. Single cell analyses are uncovering the molecular diversity of cells,...
3.
Sullivan A, Santos S
STAR Protoc
. 2020 Oct;
1(2):100062.
PMID: 33000002
Chromatin immunoprecipitation (ChIP) followed by next-generation sequencing is a powerful technique that characterizes the genome-wide DNA-binding profile of a protein of interest. The general ChIP-seq workflow has been applied widely...
4.
Lockhead S, Moskaleva A, Kamenz J, Chen Y, Kang M, Reddy A, et al.
Cell Rep
. 2020 Jul;
32(2):107901.
PMID: 32668239
Protein synthesis inhibitors (e.g., cycloheximide) block mitotic entry, suggesting that cell cycle progression requires protein synthesis until right before mitosis. However, cycloheximide is also known to activate p38 mitogen-activated protein...
5.
Padgett J, Santos S
FEBS Lett
. 2020 Jun;
PMID: 32535913
Cell division is a fundamental cellular process and the evolutionarily conserved networks that control cell division cycles adapt during development, tissue regeneration, cell de-differentiation and reprogramming, and a variety of...
6.
Gunne-Braden A, Sullivan A, Gharibi B, Sheriff R, Maity A, Wang Y, et al.
Cell Stem Cell
. 2020 Apr;
26(5):693-706.e9.
PMID: 32302522
During early development, extrinsic triggers prompt pluripotent cells to begin the process of differentiation. When and how human embryonic stem cells (hESCs) irreversibly commit to differentiation is a fundamental yet...
7.
Araujo A, Gelens L, Sheriff R, Santos S
Mol Cell
. 2016 Oct;
64(2):362-375.
PMID: 27768873
Cell division is characterized by a sequence of events by which a cell gives rise to two daughter cells. Quantitative measurements of cell-cycle dynamics in single cells showed that despite...
8.
Santos S, Wollman R, Meyer T, Ferrell Jr J
Cell
. 2012 Jun;
149(7):1500-13.
PMID: 22726437
Mitosis is triggered by the activation of Cdk1-cyclin B1 and its translocation from the cytoplasm to the nucleus. Positive feedback loops regulate the activation of Cdk1-cyclin B1 and help make...
9.
10.
Santos S, Verveer P, Bastiaens P
Nat Cell Biol
. 2007 Feb;
9(3):324-30.
PMID: 17310240
The mitogen-activated protein kinase (MAPK) network is a conserved signalling module that regulates cell fate by transducing a myriad of growth-factor signals. The ability of this network to coordinate and...